Strata EXPress™: A Study Using StrataEXP™ to Identify RNA-Expression Biomarkers in Advanced Cancer Patients

Inclusion Criteria:

1. Must be ≥18 years of age,
2. Participant must have pathologically confirmed advanced, metastatic, or recurrent solid tumor,
3. Measurable disease,
4. Eastern Cooperative Oncology Group (ECOG) performance status score of 0-2,
5. Participant must meet at least 1 of the following:

   1. Is/has not adequately responded to standard therapy, or
   2. For whom no life-extending standard therapy exists, or
   3. Who decline standard therapy, or
   4. In the opinion of the investigator, is not a candidate for or would be unlikely to tolerate or derive significant clinical benefit from standard therapy
6. Adequate cardiac, bone marrow, organ function \& laboratory parameters as determined by the treating physician for potential participation in a clinical trial,
7. Leftover formalin-fixed, paraffin-embedded (FFPE) tumor tissue available for StrataEXP testing

Exclusion Criteria:

1. Females who are pregnant or nursing,
2. History of stroke including transient ischemic attack (TIA) or acute myocardial infarction within 4 months of enrollment,
3. Any other clinically significant medical condition that, in the opinion of the treating physician, makes participation in a clinical trial undesirable, including but not limited to ongoing or active infection, significant uncontrolled hypertension, or severe psychiatric illness.