Clinical trial · Interventional
Chemoprophylaxis With Rivaroxaban for Lower Limb Deep Vein Thrombosis in Colorectal Cancer
Evaluation of Chemoprophylaxis With Rivaroxaban for Lower Limb Deep Vein Thrombosis in the Surgical Treatment of Colorectal Cancer
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The chemoprophylaxis of deep vein thrombosis (DVT) with subcutaneous low-molecular-weight heparin (enoxaparin) in the postoperative period of elective surgeries is already well established in the literature and in clinical practice. However, the use of this medication can have a financial impact on the patient and the parenteral presentation itself is associated with pain at the application site, which can make it difficult for patients to adhere.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Colonic Cancer | — | UNRESOLVED | — |
| Deep Venous Thrombosis | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Rivaroxaban 10 MG | Drug | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- EXPERIMENTAL
- label
- post-operative patients with colonic cancer
- description
- Patients will receive Rivaroxaban 10mg/daily for 28 days after surgery. Only one arm.
- interventionNames
- Drug: Rivaroxaban 10 MG
Primary outcomes (1)
- measure
- Deep venous thrombosis and embolic pulmonary disease
- timeFrame
- 28 days after surgery
- description
- Patients will evaluated with Duplex ultrasound. Duplex ultrasound using b mode and compressibility. All patients will be evaluated.
Secondary outcomes (1)
- measure
- Safety of rivaroxaban
- timeFrame
- 28 days after surgery
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 90 Years
Show eligibility criteria text
Inclusion Criteria: * Patients in post-operative surgery for colonic cancer. * No contraindication for anticoagulation usage. * Absence of renal or hepatic failure. Exclusion Criteria: * Pregnancy, * age \< 18 years, * contraindication to the use of anticoagulants, -failure to complete the informed consent form. -
References
Publications (0)
Data not yet available