Clinical trial · Interventional
Fluoroscopic Anterior Approach Versus Ultrasound Guided Superior Hypogastric Plexus Neurolysis in Cancer Pelvic Pain
NCT05299047CI-TRIAL-00060342unknownPhase 2ClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Cancer related pelvic pain can be debilitating and difficult to treat. Superior hypogastric plexus neurolysis (SHPN) is considered to be an option for adequately relieving pain, with fewer side effects and improving the quality of life
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Pain Cancer | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Group fluoroscopy-guided | Other | — | UNRESOLVED |
| Group US-guided | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- ACTIVE_COMPARATOR
- label
- Group US-guided
- description
- will receive superior hypogastric plexus neurolysis by the US-guided anterior approach
- interventionNames
- Other: Group US-guided
- type
- ACTIVE_COMPARATOR
- label
- - Group fluoroscopy-guided
- description
- will receive superior hypogastric plexus neurolysis by the fluoroscopy-guided anterior approach
- interventionNames
- Other: Group fluoroscopy-guided
Primary outcomes (4)
- measure
- The symptom burden was evaluated using the Edmonton Symptom Assessment System (ESAS)
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 70 Years
Show eligibility criteria text
Inclusion Criteria: * Patients more than 18 years old of both genders with cancer-related pelvic pain, * poor pain control or severe side effects with opioid therapy, * ≥ 4 on a numeric rating scale (NRS) of pain that ranged from 0 (no pain) to 10 (extreme pain)., * American society of Anesthesiology Physical Status class I and II, * positive diagnostic block day before the procedure by injecting a local anesthetic (0.25% bupivacaine 10 ml) * Body mass index ˂ 30 were included in this study. Exclusion Criteria: * patient refusal, * local or systemic sepsis, * coagulopathy, * unstable cardiovascular and respiratory diseases, * previous neurological deficits, * history of psychiatric disorders, * history of drug abuse, * distorted local anatomy, * those who were allergic to the used medications were excluded from the study.
References
Publications (1)
- DERIVEDAbdelghaffar NA, Farahat TE. Fluoroscopic anterior approach versus ultrasound guided superior hypogastric plexus neurolysis in cancer pelvic pain: a randomized controlled study. BMC Anesthesiol. 2022 Dec 27;22(1):403. doi: 10.1186/s12871-022-01948-3. PMID 36575390