Clinical trial · Observational
Circulating Tumor Cell Detection in Hepatocellular Carcinoma
A Retrospective Study of Data Related to Circulating Tumor Cell Detection in Hepatocellular Carcinoma
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The investigators examined circulating tumor cells (CTC) in the perioperative peripheral blood of hundreds of HCC patients undergoing liver cancer surgery using CellSearch technology between 2013 and 2016. Although the investigators have done a preliminary study of the above data and published some results, the previous study was only a basic analysis. Now the investigators plan to carry out further in-depth analysis of these data, including hospitalization data, follow-up results, surgical tumors and blood specimens, and make full use of biostatistics, molecular biology, pathology and other related techniques to elucidate the association between the levels of CTC or CTC clusters and patients' disease during the perioperative period, and to explore the molecular basis of CTC production in hepatocellular carcinoma.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Circulating Tumor Cell | — | UNRESOLVED | — |
Interventions
Interventions (0)
Data not yet available
Design
Arms and outcomes
Arms (2)
- label
- The number of CTC in HCC patient great than or equal to two
- description
- According to the cutoff of CTC, the number of CTC in HCC patient great than or equal to two
- label
- The number of CTC in HCC patient less than two
- description
- According to the cutoff of CTC,the number of CTC in HCC patient less than two
Primary outcomes (1)
- measure
- Data analysis of relationship between CTC and pathological indicators of hepatocellular carcinoma
- timeFrame
- 2022.03.15
- description
- The previous CTC detection data of 458 cases was collected. To compare the relationship between CTC level of perioperative peripheral blood and clinical indexes of HCC patients, the main statistical analysis were one-way ANOVA, Student's T test and Multivariable Cox regression.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 80 Years
Show eligibility criteria text
Inclusion Criteria: * The pathological diagnosis was primary liver cancer. * Undergoing radical surgical treatment * No preoperative antitumor therapy was received * Between 18 and 80 years old Exclusion Criteria: * With distal metastasis * With other tumors * Perioperative death * Recurrence within one month after surgery * Lost contact before the first follow-up
References
Publications (0)
Data not yet available