Clinical trial · Interventional
Pectoralis Nerve Block and Quality of Recovery in Mastectomy Patients
The Effect of Pectoralis Nerve Block on Quality of Recovery in Patients Undergoing Breast-conservative Surgery
NCT05266378CI-TRIAL-00063354unknownN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Effects of pectoralis nerve block on quality of recovery after breast surgery has been debated. We hypothesized there might exist relevant psychosocial factor or variable of pain sensitivity which would influence on the benefit of nerve block. This study aims to assess effect of pectoralis nerve block on QoR-15 score in subgroups stratified by such factors.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Breast Cancer | Malignant Breast Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Not receiving PECs Block | Other | — | UNRESOLVED |
| PECs block | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Block group
- description
- The group undergoing PECs block
- interventionNames
- Procedure: PECs block
- type
- PLACEBO_COMPARATOR
- label
- Control group
- description
- The group not receiving PECs block
- interventionNames
- Other: Not receiving PECs Block
Primary outcomes (1)
- measure
- QoR-15
- timeFrame
- Postoperative day 1
- description
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 20 Years
- Maximum age
- 80 Years
Show eligibility criteria text
Inclusion Criteria: * Patients aged 20 to 80 years who underwent partial mastectomy for breast cancer. Exclusion Criteria: * Patients with a history of previous breast surgery * Patients with a history of adverse reactions to local anesthetics * Patients with a history of drug addiction * Patients with cancer other than breast * Patients with chronic pain who require analgesics * History of hospitalization for psychiatric disorders * Preoperative pulse oximetry (SpO2) \< 95 % * Left ventricular ejection fraction \< 40% * Moderate or severe hepatic impairment * Body mass index over 35 kg/m2 * Blood clotting disorders * Pregnant/lactating women * Inability to understand consent forms and answer research questionnaires due to cognitive impairment * Unable to read consent form (eg illiterate, foreigner, etc.) * do not perform axillary lymph node dissection
References
Publications (1)
- BACKGROUNDAbdallah FW, Patel V, Madjdpour C, Cil T, Brull R. Quality of recovery scores in deep serratus anterior plane block vs. sham block in ambulatory breast cancer surgery: a randomised controlled trial. Anaesthesia. 2021 Sep;76(9):1190-1197. doi: 10.1111/anae.15373. Epub 2021 Jan 25. PMID 33492696