Clinical trial · Interventional
Effects of Music Intervention Combined With Progressive Muscle Relaxation in Cancer Patients
Effects of Music Intervention Combined With Progressive Muscle Relaxation on Anxiety, Depression and Quality of Life in Breast and Gynaecological Cancer Patients Receiving Chemotherapy: A Randomized Controlled Trial
NCT05262621CI-TRIAL-00065589completedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Study design A 2-arm, assessor-blinded randomised controlled trial will be conducted. The design will follow the Standard Protocol Items Recommendations for Interventional Trials (SPIRIT)
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cancer | Malignant Neoplasm | ALIAS | 0.90 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Listening to relaxing music once/day | Other | — | UNRESOLVED |
| progressive muscle relaxation | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Music intervention combined with progressive muscle relaxation
- description
- Music intervention combined with progressive muscle relaxation.
- interventionNames
- Other: progressive muscle relaxation
- Other: Listening to relaxing music once/day
- type
- NO_INTERVENTION
- label
- Control group
- description
- no music therapy will be done.
Primary outcomes (2)
- measure
- Change from baseline anxiety at 3 weeks and 6 weeks
- timeFrame
- ebaseline, T1 after 3 weeks, T2 after 6 weeks
- description
- it will be measured using the short form of the Depression Anxiety Stress Scale (DASS-21). It includes 7 items for anxiety (DASS21-A). A 4-point Likert-type scale ranging from 0 to 3 was designed for each item, and the scores will need to be multiplied by 2 to calculate the final score. Thus, the anxiety score can range from 0 to 42. The higher the score is the more severe anxiety. The score of 0-7 is normal, 8-9 mild, 10-14 moderate, 15-19 severe, +20 extremely severe.
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Women with breast or gynaecological cancer are 18 years of age or older, and are independent legally to sign the consent form. * Living with family and having an adult family member agree to participate in the meeting part of the program. * Had been informed the cancer diagnosis * Have Karnofsky score (Mor et al., 1984) ≥ 80 ( to be able to self-practice MCP) * Can communicate, read and write in Vietnamese * Have a device such as a smartphone, MP3 to keep the audio file (to self-practice MCP at home) * Consent to join the study Exclusion Criteria: * The patients cannot understand the study procedures * Have mental health illness, deafness, blindness * Have not been aware of their cancer or the purpose of chemotherapy * Be participating in other studies related to psychological issues * Be receiving anxiety or depression treatment. * Be participating in relaxation therapy such as yoga, meditation, mindfulness, PMR... * Have a potential treatment (eg. surgery) or personal plans that will prevent them from practising daily during the 6 weeks of the intervention.
References
Publications (2)
- DERIVEDNguyen KT, Chan DNS, Cheung AT, Hoang HTX, Truong AT, Chow KM, Choi KC, Chan CWH. Randomised controlled trial of music listening combined with progressive muscle relaxation for mood management in women receiving chemotherapy for cancer. Support Care Cancer. 2025 Mar 4;33(3):245. doi: 10.1007/s00520-025-09281-4. PMID 40035884
- DERIVEDNguyen KT, Hoang HTX, Bui QV, Chan DNS, Choi KC, Chan CWH. Effects of music intervention combined with progressive muscle relaxation on anxiety, depression, stress and quality of life among women with cancer receiving chemotherapy: A pilot randomized controlled trial. PLoS One. 2023 Nov 3;18(11):e0293060. doi: 10.1371/journal.pone.0293060. eCollection 2023. PMID 37922279