Clinical trial · Interventional
Improving Cyberknife Spinal Stereotactic Radiotherapy in Difficult to Treat Cases (IMPRESS)
NCT05252975CI-TRIAL-00056696IMPRESSunknownN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
A prospective study evaluating prone and supine positioning for radiation planning of spine Cyberknife radiotherapy treatment. Patients with tumours in which PTV coverage is compromised due to tumour geography, including posteriorly based lesions in the vertebral column and close proximity to organ at risk (other than the spinal cord).
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Solid Tumor, Adult | Adult Solid Neoplasm | ALIAS | 0.90 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Setup and Imaging for at CT radiation planning | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- ACTIVE_COMPARATOR
- label
- Supine
- description
- Patients undergo supine setup and imaging for radiation planning
- interventionNames
- Other: Setup and Imaging for at CT radiation planning
- type
- EXPERIMENTAL
- label
- Prone
- description
- Patients undergo prone setup and imaging for radiation planning
- interventionNames
- Other: Setup and Imaging for at CT radiation planning
Primary outcomes (1)
- measure
- PTV isodose coverage
- timeFrame
- Through study completion, an average of 1 year.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * • Patients undergoing Cyberknife treatment to spinal metastasis * \>18 years of age * Thoracic, lumbar and sacral spinal metastasis * Patients suitable to undergo radiotherapy planning CT scans in the prone position (treating physician assessed as having spinal stability). * All solid tumour types will be eligible Exclusion Criteria: * • Primary spinal tumours * Vertebral disease resulting in unstable spinal vertebrae * Cervical tumours (patients will be unable to have a thermoplastic shell made for the prone position). * Patients with significant pain on prone lying (to be assessed by physician prior to consent) * Bilsky epidural score of 2 or greater (see appendix 1) * Pre-existing musculoskeletal chronic back medical diagnoses that would preclude CT scanning in the prone position.
References
Publications (0)
Data not yet available
No reference posted for this study.