Clinical trial · Interventional
Evaluation of the Patient Experience With a Surgically-assisted Acceleration Method of Orthodontic Treatment
The Effect of Corticision on Perceived Pain and Discomfort for Patients With Crowded Lower Anterior Teeth in Young Adult Patients: Randomized Clinical Trial
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The duration of orthodontic treatment is one of the exacerbation causes of orthodontic pain. Several methods have been suggested to reduce the duration of orthodontic treatment classified to surgical and non-surgical methods. Researches used minimally invasive surgical methods like corticision, piezocesion, disicion, micro-osteoperforation, and piezopuncture indicated that most of these methods can accelerate dental movement by 20 - 40% without causing additional pain as a result of using those methods. Applying corticision on the lower anterior teeth using a surgical blade and a hammer may accelerate tooth alignment during orthodontic treatment. This study consists of two groups, patients will be randomly assigned to one of these two groups.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Crowding, Tooth | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Conventional fixed appliance | Device | — | UNRESOLVED |
| Corticision | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Corticision
- description
- Corticision will be performed on the lower anterior teeth using a surgical blade and a hammer.
- interventionNames
- Procedure: Corticision
- type
- ACTIVE_COMPARATOR
- label
- Conventional method
- description
- A fixed appliance will be applied using conventional braces without any surgical procedure.
- interventionNames
- Device: Conventional fixed appliance
Primary outcomes (5)
- measure
- Change in the levels of pain
- timeFrame
- at 1, 7, 14 days following the onset of orthodontic treatment
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 24 Years
Show eligibility criteria text
Inclusion Criteria: 1. Age range between 18 and 24 years 2. Completion of permanent dentition (except third molars) 3. Mild to moderate crowding (2-6 mm according to Little's index) 4. Absence of medications intake that interferes with pain perception for at least one week before the beginning of the treatment Exclusion Criteria: 1. Systematic diseases that could affect bone and tooth movement and no contraindication avoid oral surgery 2. Medical conditions that affect tooth movement (Corticosteroid, NSAIDs) 3. Patients had previous orthodontic treatments 4. Poor oral hygiene or concurrent periodontal disease
References
Publications (5)
- BACKGROUNDGibreal O, Hajeer MY, Brad B. Evaluation of the levels of pain and discomfort of piezocision-assisted flapless corticotomy when treating severely crowded lower anterior teeth: a single-center, randomized controlled clinical trial. BMC Oral Health. 2019 Apr 16;19(1):57. doi: 10.1186/s12903-019-0758-9. PMID 30991984
- BACKGROUNDAlkebsi A, Al-Maaitah E, Al-Shorman H, Abu Alhaija E. Three-dimensional assessment of the effect of micro-osteoperforations on the rate of tooth movement during canine retraction in adults with Class II malocclusion: A randomized controlled clinical trial. Am J Orthod Dentofacial Orthop. 2018 Jun;153(6):771-785. doi: 10.1016/j.ajodo.2017.11.026. PMID 29853235
- BACKGROUNDCharavet C, Lecloux G, Bruwier A, Rompen E, Maes N, Limme M, Lambert F. Localized Piezoelectric Alveolar Decortication for Orthodontic Treatment in Adults: A Randomized Controlled Trial. J Dent Res. 2016 Aug;95(9):1003-9. doi: 10.1177/0022034516645066. Epub 2016 Apr 29. PMID 27129491
- BACKGROUNDYavuz MC, Sunar O, Buyuk SK, Kantarci A. Comparison of piezocision and discision methods in orthodontic treatment. Prog Orthod. 2018 Oct 29;19(1):44. doi: 10.1186/s40510-018-0244-y. PMID 30370430
- BACKGROUNDUribe F, Davoody L, Mehr R, Jayaratne YSN, Almas K, Sobue T, Allareddy V, Nanda R. Efficiency of piezotome-corticision assisted orthodontics in alleviating mandibular anterior crowding-a randomized clinical trial. Eur J Orthod. 2017 Nov 30;39(6):595-600. doi: 10.1093/ejo/cjw091. PMID 28371882