Clinical trial · Observational
Evaluation of Infective Risk, Efficacy of Bacterial Prophylaxis and Validation of Sepsis Scores NEWS (National Early Warning Score) and qSOFA (Quick Sequential Organ Failure Assessment) in Patient With Acute Myeloid Leukemia Treated With Intensive Chemotherapy
Evaluation of Infective Risk, Efficacy of Bacterial Prophylaxis and Validation of Sepsis Scores NEWS (National Early Warning Score) and qSOFA (Quick Sequential Organ Failure Assessment) in Patient With Acute Myeloid Leukemia Treated With Intensive Chemotherapy (LAM-SEPSIS)
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Evaluation of Infective Risk, Efficacy of Bacterial Prophylaxis and Validation of sepsis scores NEWS (National Early Warning Score) and qSOFA (Quick Sequential Organ Failure Assessment) in Patient With Acute Myeloid Leukemia Treated With Intensive Chemotherapy
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Acute Myeloid Leukemia | Acute Myeloid Leukemia | CURATED_BROADER | 0.80 |
Interventions
Interventions (0)
Data not yet available
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (1)
- measure
- Mortality risk
- timeFrame
- At baseline (fever onset), change at 24 hours from baseline, change at 48 hours from baseline
- description
- Ability of NEWS and qSOFA score to predict mortality risk calculating the area under the ROC (receiver operating characteristics) curve called AUROC (area under the ROC curve)
Secondary outcomes (7)
- measure
- Systemic Inflammatory Response Syndrome (SIRS) development
- timeFrame
- At baseline (fever onset), change at 24 hours from baseline, change at 48 hours from baseline
- description
- Ability of NEWS and qSOFA score to predict SIRS development calculating the area under the ROC (receiver operating characteristics) curve called AUROC (area under the ROC curve)
- measure
- Amine requirement
- timeFrame
- At baseline (fever onset), change at 24 hours from baseline, change at 48 hours from baseline
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 70 Years
Show eligibility criteria text
Inclusion Criteria: * Diagnosis of non M3 Acute Myeloid Leukemia according to WHO (World Health Organization) 2008 criteria * Age \>= 18 years and \<= 70 years * Patient had received intensive chemotherapy either as induction or consolidation regimen * Period of observation: January 2001 - December 2019 * Written informed consent Exclusion Criteria: * Diagnosis of Acute Promyelocytic Leukemia (M3 AML) * Age \< 18 or \>70 years * Patient had not received intensive chemotherapy
References
Publications (0)
Data not yet available