Clinical trial · Observational
Living Donor Liver Transplant for Unresectable Colorectal Liver Metastases
Liver Transplantation From Living Donors For Treatment Of Non-Resectable Colorectal Carcinoma Liver Metastases: A Registry Study
NCT05248581CI-TRIAL-00118620recruitingClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The goal of this study is to create a data registry to capture clinical, pathologic, and molecular data/outcomes for patients with metastatic colorectal cancer who undergo live donor liver transplantation.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Colorectal Cancer Metastatic | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Liver transplantation | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- All Participants
- description
- Potential subjects for this registry must have Stage IV colorectal cancer with liver metastases and be candidates for liver transplantation based on multidisciplinary discussion by the Liver transplantation team. Patients must demonstrate favorable tumor biology and no evidence of extra hepatic disease.
- interventionNames
- Procedure: Liver transplantation
Primary outcomes (2)
- measure
- percentage of patients with recurrence free survival
- timeFrame
- 5 years
- description
- RFS proportions to be calculated at 1, 3, and 5 years with Kaplan Meier analysis
- measure
- percentage overall survival
- timeFrame
- 5 years
- description
- OS proportions to be calculated at 1, 3, and 5 years with Kaplan Meier analysis
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Age ≥ 18 * Non-amenable to curative hepatic resection as defined by FLR \<30% * Histologically confirmed adenocarcinoma of the colon or rectum * Candidate for LDLT for colorectal liver metastasis per the University of Rochester liver transplant program Exclusion Criteria: * Not a candidate of the LDLT liver transplant protocol for treatment of colorectal liver metastasis. * Unwilling to consent
References
Publications (0)
Data not yet available
No reference posted for this study.