Clinical trial · Observational
Exercise Capacity and Physical Activity Level in Prolactinoma Patients
Comparison of Exercise Capacity, Physical Activity Level and Quality of Life in Prolactinoma Patients and Healthy Individuals
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Prolactinoma, one of the most common pituitary adenomas, is an adenoma that causes excessive prolactin (PRL) secretion. An increase in prolactin level can cause weakness, decrease in muscle mass and fatigue. It is not known in detail to what extent it affects quality of life, functional exercise capacity, cardiovascular disease risk factors, physical activity level, fatigue and sleep quality in prolactinoma patients. It is aimed to compare how much exercise capacity, physical activity level, sleep quality, perception of fatigue and quality of life of prolactinoma patients are affected compared to healthy individuals and to examine the factors associated with exercise capacity in prolactinoma patients.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Prolactinoma | Lactotroph Pituitary Neuroendocrine Tumor | ALIAS | 0.90 |
Interventions
Interventions (0)
Data not yet available
Design
Arms and outcomes
Arms (2)
- label
- Healthy group
- description
- Healthy women aged 18-55 who have not been diagnosed with any chronic disease and pituitary adenoma
- label
- Patient with Prolactinoma group
- description
- Women between the ages of 18-55 diagnosed with Prolactinoma
Primary outcomes (3)
- measure
- Aerobic Exercise Capacity
- timeFrame
- day 1
- description
- Exercise capacity levels of individuals will be evaluated with the 6-Minute Walking Test (6MWT).
- measure
- Physical Activity Level
- timeFrame
- day 1
- description
- Physical activity level will be evaluated with the Turkish version of the short form of the International Physical Activity Questionnaire (IPAQ). The scale consists of 7 questions. Activities and sitting time in the last 1 week are recorded in minutes.
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
- Maximum age
- 55 Years
Show eligibility criteria text
Inclusion Criteria of patients: * Being between the ages of 18-55 * Woman * Being diagnosed with prolactinoma * Volunteering to participate in the study Exclusion Criteria of the patients : * Patients with neurological, cognitive or orthopedic disease that will affect the measurements * Patients with severe respiratory disease (FEV1 \< 35%; FVC \< 50%) * Presence of acute infection * Presence of malignancy * Presence of dementia * Patients who have had a cardiovascular event in the last 6 months * Less than 50% of the ejection fraction * Patients with uncontrolled hypertension * Individuals with a diagnosis of uncontrolled diabetes mellitus will not be included in the study. Healthy group inclusion criteria: * Being between the ages of 18-55 * Woman * Not being diagnosed with any pituitary adenoma * Volunteering to participate in the study Healthy group exclusion criteria: * Cases with neurological, cognitive or orthopedic diseases that will affect the measurements * Cases with severe respiratory disease (FEV1 \< 35%; FVC \< 50%) * Presence of acute infection * Presence of malignancy * Presence of dementia * Cases who have had a cardiovascular event in the last 6 months * Less than 50% of the ejection fraction * Patients with uncontrolled hypertension * Cases with uncontrolled diabetes mellitus diagnosis will not be included in the study.
References
Publications (1)
- DERIVEDErkoc A, Eroglu I, Erbas T, Kutukcu EC. Muscle function, exercise capacity, physical activity level and cardiovascular disease risk factor knowledge in patients with prolactinoma. Endocrine. 2024 Sep;85(3):1337-1345. doi: 10.1007/s12020-024-03880-7. Epub 2024 May 27. PMID 38801597