Clinical trial · Observational
HIV Indicator Diseases in Hospital and Primary Care
Supporting Health Care Professionals in Hospital and Primary Care to Promote Adequate HIV Risk and Indicator Condition Driven Testing in Routine Care.
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Patients are frequently evaluated by physicians for medical work-up of HIV indicator conditions in hospital and in primary care at the general practitioner. Testing for HIV is indicated with HIV indicator disorder but often omitted in clinical work-up. Besides the fact that HIV testing is forgotten, there are other reasons such as an underestimation of the risk of HIV in the event of indicator disorders, stigma and difficulties in discussing the test with a patient. Also and more relevant for primary care than for the hospital, practical challenges can exist for a patient to go to a laboratory, or costs are a hurdle. This project focuses on improving HIV indicator condition driven testing in different settings of the HIV epidemic, initially in the Netherlands as low HIV prevalence setting followed by an assessment of its benefit in different international settings. A specific focus will also be on the Rotterdam area in the Netherlands which has a high prevalence of undiagnosed HIV in the Netherlands. The ultimate aim is to decrease the number of undiagnosed HIV in populations, improve the 90-90-90 HIV cascade of care goals particularly its first pillar, and to help supporting the UNAIDS goal to end HIV/AIDS
Conditions
Conditions (18)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Acquired Immunodeficiency Syndrome | — | UNRESOLVED | — |
| AIDS Defining Illness | — | UNRESOLVED | — |
| Candida Infection | — | UNRESOLVED | — |
| Dermatitis, Seborrheic | — | UNRESOLVED | — |
| Diarrhea Chronic | — | UNRESOLVED | — |
| Herpes Zoster | — | UNRESOLVED | — |
| HIV Indicator Condition | — | UNRESOLVED | — |
| HIV Infections | — | UNRESOLVED | — |
| Infectious Mononucleosis | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| HIV rapid test | Diagnostic Test | — | UNRESOLVED |
| Peer to peer feedback | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- label
- Hospital
- description
- Medical specialists in hospitals and their patients aged 18 years and older in the participating hospitals who are diagnosed there with an HIV indicator condition.
- interventionNames
- Behavioral: Peer to peer feedback
- label
- Primary care
- description
- General practitioners and their patients aged 18 years and older in the participating general practices who are diagnosed there with an HIV indicator condition.
- interventionNames
- Behavioral: Peer to peer feedback
- Diagnostic Test: HIV rapid test
Primary outcomes (2)
- measure
- The number of adequately performed HIV tests of identified HIV indicator conditions in relation to the total number of identified HIV indicator conditions by physicians in hospital settings during the project.
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Diagnosis of an HIV indicator conditions. Exclusion Criteria: * Below 18 years of age * Recent HIV test (\< 12 months, except for mononucleosis-like disease and STDs)
References
Publications (1)
- DERIVEDJordans CCE, Niemantsverdriet-Rokx L, Struik JL, van der Waal EC, van der Voorn PVJM, Bakker N, Verbon A, Bindels PJE, Rokx C. Implementing HIV teams to improve HIV indicator condition-guided testing in general practitioner centers in the Netherlands. BMC Prim Care. 2024 Dec 27;25(1):440. doi: 10.1186/s12875-024-02666-0. PMID 39731054