Clinical trial · Observational
Investigating the Diagnostic Potential of Tear Proteins in Cancer - A Pilot Study
Investigating the Diagnostic Potential of Tear Proteins in Breast, Ovarian, Prostate, Melanoma, Pancreatic, and Colon Cancer
NCT05223218CI-TRIAL-00067722unknownClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This Pilot Study is to investigate the tear proteins in a multitude of cancer types and indulge in biomarker discovery to manufacture simple, accurate, and novel tear-based diagnostic tests.
Conditions
Conditions (5)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Breast Cancer | Malignant Breast Neoplasm | CURATED_EXACT | 0.92 |
| Melanoma | Melanoma | ONTOLOGY_EXACT | 0.98 |
| Ovarian Cancer | Malignant Ovarian Neoplasm | CURATED_EXACT | 0.92 |
| Pancreatic Cancer | Malignant Pancreatic Neoplasm | CURATED_EXACT | 0.92 |
| Prostate Cancer | Malignant Prostate Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Schirmer strip, a Class I Medical Device typically used to test for dry eye. | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (6)
- label
- Breast Cancer
- description
- Individuals aged between 18-100 years who are presenting for an evaluation of an abnormal exam or test (Mammogram, ultrasound, MRI, PET, etc.); presenting for the evaluation of a palpable lump or mass; presenting with a mass pre or post-biopsy as long as there is a portion of the mass remaining; or have been diagnosed with breast cancer but have not received treatment. Lacrimal tear fluid samples are collected using a Schirmer strip, a Class I Medical Device typically used to test for dry eye.
- interventionNames
- Other: Schirmer strip, a Class I Medical Device typically used to test for dry eye.
- label
- Pancreatic Cancer
- description
- Individuals aged between 18-100 years who are presenting for an evaluation of an abnormal exam or test (Ultrasound, MRI, PET, etc.); presenting for the evaluation of a palpable lump or mass; presenting with a mass pre or post-biopsy as long as there is a portion of the mass remaining; or have been diagnosed with breast cancer but have not received treatment. Lacrimal tear fluid samples are collected using a Schirmer strip, a Class I Medical Device typically used to test for dry eye.
- interventionNames
- Other: Schirmer strip, a Class I Medical Device typically used to test for dry eye.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 100 Years
Show eligibility criteria text
Inclusion Criteria: * 18-100 years of age * Presenting for the evaluation of an abnormal exam or test (mammogram, ultrasound, MRI, PET, etc.) * Presenting for the evaluation of a palpable lump or mass * Presenting with a mass may be pre or post-biopsy/diagnostic as long as there is a portion of the mass remaining. * Have been diagnosed but have not received treatment Exclusion Criteria: * Less than 18 years of age OR more than 100 years of age * Concurrent eye infection or trauma * Acute conjunctivitis
References
Publications (0)
Data not yet available
No reference posted for this study.