Clinical trial · Interventional
Sexual Health in Patients With Hematologic Malignancies
Sexual Health in Patients With Hematologic Malignancies - Symptom Assessment and Management
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Sexual wellbeing is an integral component of psychosocial and physical wellbeing. Cancer-related symptoms, treatment side-effects and psychosocial distress have significant impact on sexual well-being and sexual health. Within the framework of sexual wellbeing, sexual function is defined by a capacity to fully engage in all phases of the human sexual response cycle. Thus, sexual dysfunction is characterized by a disruption in one or more elements of the response cycle. Previous research shows that patients with hematologic malignancies and specifically patients following stem cell transplantation experience a high symptom burden and distinct genital alterations, and therefore in increased risk of sexual dysfunction. In spite of growing evidence documenting high prevalence of sexual dysfunction in cancer patients, patients with hematologic malignancies are underrepresented in clinical trials investigating their sexual health. This study aims to examine the sexual health in patients across hematologic malignancies in Denmark, and to investigate feasiblity and effect of a randomized multimodal intervention by providing nurse-led sexual consultations and physician-led preventive genital examinations, to enhance sexual function and early recognition of gential graft versus host disease in adult patients following hematopoietic stem cell transplantation. Finally, the study aims to explore perspectives and experiences of patients following this multimodal intervention. This knowledge will entail new opportunities to detect subgroups of patients with distinct risk of sexual dysfunction, and potentially lead to targeted interventions in clinical practice toward this specific population. Moreover this will provide evidence with high methodological rigor and potentially strengthen the possibilities for evidence-based decision making in Denmark regarding preventive gential examinations during follow-up in patients following stem cell transplant.
Conditions
Conditions (5)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Psychological | — | UNRESOLVED | — |
| Quality of Life | — | UNRESOLVED | — |
| Sexual Dysfunction | — | UNRESOLVED | — |
| Sexuality | — | UNRESOLVED | — |
| Symptoms and Signs | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Sexual Health | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Intervention
- description
- Intervention with 1. nurseled sexual consultations with screening questionnaire prior to consultation 2. genital examintaion with doctor
- interventionNames
- Other: Sexual Health
- type
- OTHER
- label
- Kontrol
- description
- Usual care
- interventionNames
- Other: Sexual Health
Primary outcomes (2)
- measure
- sexual function
- timeFrame
- 18 month
- description
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Patients (age\>18 years) with a hematologic malignancy who is planned to undergo an HSCT, who provide informed written consent and can understand, speak and read Danish are eligible to participate. Exclusion Criteria: * The exclusion criteria include patients with dementia, psychotic disorders, or other cognitive diseases or conditions that hinder participation.
References
Publications (1)
- DERIVEDNorskov KH, Schjoedt I, Tolver A, Jarden M. Sexual health in patients with malignant hematological disease: a Danish cross-sectional study. Sex Med. 2024 Sep 13;12(4):qfae053. doi: 10.1093/sexmed/qfae053. eCollection 2024 Aug. PMID 39281809