Clinical trial · Observational
Prognostic Value of Sarcopenia and Nutritional Status in Early-stage Non-small Cell Lung Cancer
Prognostic Value of Sarcopenia and Nutritional Status in Early-stage Non-small Cell Lung Cancer (Stage IA to IIIA)
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Growing evidence has confirmed that the prognosis of lung cancer is not only related to the stage of disease, but also to the physiological and psychological situation of the patients. Malignant tumors are often associated with weakness and cachexia, leading to less physical activities and worse moods. However, few studies that have attempted to investigate the impact of nutritional status on the prognosis of NSCLC. Existing applications of nutritional scoring systems in early-stage of NSCLC are very limited. Therefore, this study aims to observe the correlation between nutritional status and the prognosis of patients with early-stage NSCLC, to clarify the value in predicting the overall survival rate and progression-free survival rate of NSCLC patients, and to offer evidence for alleviating the social and economic burden of NSCLC.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Malnutrition | — | UNRESOLVED | — |
| Non Small Cell Lung Cancer | Lung Non-Small Cell Carcinoma | ALIAS | 0.90 |
| Sarcopenia | — | UNRESOLVED | — |
Interventions
Interventions (3)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| CT scan | Radiation | — | UNRESOLVED |
| Inbody 570 | Device | — | UNRESOLVED |
| JAMAR Dynamometer | Device | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- label
- Early-stage NSCLC with sarcopenia
- description
- Patients diagnosed with NSCLC meeting Stage IA-IIIA as well as sarcopenia by the enrollment
- interventionNames
- Device: Inbody 570
- Device: JAMAR Dynamometer
- Radiation: CT scan
- label
- Early-stage NSCLC without sarcopenia
- description
- Patients diagnosed with NSCLC meeting Stage IA-IIIA but without sarcopenia by the enrollment
- interventionNames
- Device: Inbody 570
- Device: JAMAR Dynamometer
- Radiation: CT scan
Primary outcomes (1)
- measure
- Progression Free Survival (PFS)
- timeFrame
- Follow-up were conducted every 2months during the first year and every 6 months for up to 5 years from enrollment. Progression-free survival was measured from the date of diagnosis until confirmed disease progression or death, whichever occurred first.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 85 Years
Show eligibility criteria text
Inclusion Criteria: * The patients with non-small cell lung cancer diagnosed by cytology or pathology meet the standards of clinical diagnosis and treatment guidelines for lung cancer of Chinese Medical Association (2018 Edition) * TNM staging diagnosis of lung cancer meets the stage IA-IIIA Exclusion Criteria: * Severe heart failure, acute progressive pulmonary inflammation, acute liver and kidney dysfunction in recent 2 weeks * Incomplete clinical and follow-up data or disagreement or inability to conduct regular follow-up CT imaging evaluation * A history of other malignant tumors and related tumor chemotherapy within half year, and previous history of radiotherapy * Unable to walk, fail to complete the walking test, and the risk of fall down * Unable to complete BIA examination due to pacemaker implantation and other reasons * Withdraw from the study for any reasons
References
Publications (0)
Data not yet available