Clinical trial · Observational
Gut Microbiota and Metabonomics
Multi-center and Multi-omics Mechanism Research of Gut Microbiota and Metabonomics in Borrmann Type IV Gastric Cancer
NCT05205187CI-TRIAL-00056135MBSunknownClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
To evaluate the correlation between gut microbiota and metabolites in Borrmann type IV gastric cancer; To find the effects of microflora and metabolites on target organs; To detect the mechanism of key flora and metabolite by in vitro and in vivo experiments; To construct models of gut microbiota and metabonomics by machine learning.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Gut Microbiota | — | UNRESOLVED | — |
| Metabolomics | — | UNRESOLVED | — |
| Stomach Neoplasms | Gastric Neoplasm | ALIAS | 0.90 |
Interventions
Interventions (3)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Borrmann IV patient specimen collection | Procedure | — | UNRESOLVED |
| Healthy control specimen collection | Procedure | — | UNRESOLVED |
| Non-Borrmann IV patient specimen collection | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (3)
- label
- Healthy group
- description
- Healthy people in the community.
- interventionNames
- Procedure: Healthy control specimen collection
- label
- Non-Borrmann IV group
- description
- Patients with Borrmann types I, II and III gastric cancer.
- interventionNames
- Procedure: Non-Borrmann IV patient specimen collection
- label
- Borrmann IV group
- description
- Patients with Borrmann type IV gastric cancer.
- interventionNames
- Procedure: Borrmann IV patient specimen collection
Primary outcomes (5)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 70 Years
Show eligibility criteria text
Inclusion Criteria: 1. Patients who sign informed consent. 2. Borrmann classification of gastric cancer is determined by more than 2 pathologists. 3. Patients with BMI 24-28. 4. Karnofsky (KPS) score \>80. Exclusion Criteria: 1. Patients who take any aspirin, antibiotics, prebiotics, or probiotics within 4 weeks and steroids or immunosuppressants within 6 months prior to specimen collection. 2. Patients who complicate with other malignant tumors. 3. Patients who complicate with diabetes, hypertension, heart disease and infectious diseases. 4. Patients who complicate with inflammatory bowel disease or irritable bowel syndrome. 5. Patients with metastasis.
References
Publications (0)
Data not yet available
No reference posted for this study.