Clinical trial · Observational
Analysis of Spatiotemporal Gait Parameters in Patients With Megaprosthesis.
Comparative Analysis of Spatiotemporal Gait Parameters in Patients With Distal Femoral Megaprosthesis and Healthy Subjects Using an Inertial Measurement Unit (IMU)
NCT05202873CI-TRIAL-00083594MP-GPcompletedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The main objective of the study is to evaluate spatiotemporal parameters of gait in tumoral patients with megaprosthesis of the distal femur.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Distal Femoral Musculoskeletal Tumors | — | UNRESOLVED | — |
| Megaprosthesis | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Gait analysis | Diagnostic Test | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- label
- Cases
- description
- Patients with distal femoral megaprosthesis due to musculoskeletal tumor
- interventionNames
- Diagnostic Test: Gait analysis
- label
- Control
- description
- Healthy subjects
- interventionNames
- Diagnostic Test: Gait analysis
Primary outcomes (13)
- measure
- Antero-posterior acceleration symmetry index
- timeFrame
- 3 months
- description
- This metric serves as a quantifiable measure of the symmetry exhibited in movements along the antero-posterior axis, thereby illustrating the equilibrium and coordination inherent in the body's kinetic activities.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 16 Years
- Maximum age
- 99 Years
Show eligibility criteria text
Inclusion Criteria: * Megaprosthesis of the distal femur * Tumor cause * Surgery at Hospital la Fe. * Traditional stem or biological ossteointegration system * Minimum postoperative follow-up period of 3 months Exclusion Criteria: * Neurological alterations prior to the intervention that affect the lower limbs or general movement. * Patient incapable of ambulation due to progression of his/her pathology * Patient at home with palliative treatment for advanced tumor disease * Any ipsilateral or contralateral prosthesis. * Infectious or traumatic cause
References
Publications (2)
- BACKGROUNDWilson PJ, Steadman P, Beckman EM, Connick MJ, Carty CP, Tweedy SM. Fitness, Function, and Exercise Training Responses after Limb Salvage With a Lower Limb Megaprosthesis: A Systematic Review. PM R. 2019 May;11(5):533-547. doi: 10.1002/pmrj.12045. Epub 2019 Mar 7. PMID 30844129
- BACKGROUNDMorri M, Forni C, Ruisi R, Giamboi T, Giacomella F, Donati DM, Benedetti MG. Postoperative function recovery in patients with endoprosthetic knee replacement for bone tumour: an observational study. BMC Musculoskelet Disord. 2018 Oct 2;19(1):353. doi: 10.1186/s12891-018-2280-7. PMID 30285683