Clinical trial · Observational
Study of Healthy Cohort for Early Detection of Cancer
NCT05193305CI-TRIAL-00103991recruitingClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Cancer produces a significant burden on society with a majority diagnosed at late stages when the chance of cure is low. Early diagnosis improves patient outcomes. Data consisting of lifestyle factors, medications, physical activity, years before conventional cancer diagnosis is also worthwhile for to determine early detection. This is only achievable with longitudinal tracking of a large number of healthy individuals and identifying those who do develop cancer over time.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Healthy | — | UNRESOLVED | — |
Interventions
Interventions (0)
Data not yet available
No intervention recorded.
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (1)
- measure
- Development of malignancy
- timeFrame
- Up to 20 years
- description
- Assessment of participants for the development of malignancy during a 20-year follow-up period.
Secondary outcomes (1)
- measure
- Development of biomarkers
- timeFrame
- Up to 20 years
- description
- To identify proteins, RNA and DNA that have changes in expression in those who develop cancer.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * All adults 18 years of age of older undergoing upper or lower endoscopy for routine medical care. Exclusion Criteria: * Persons with current malignancy * Persons with history of malignancy and treatment within last 5 years of enrollment, excluding non-melanoma skin cancer or cervical in-situ. * Persons who are unable or unwilling to provide repeat blood samples and complete follow-up questionnaires * Persons who lack the capacity to provide consent * Persons who do not speak English * Persons who are visually or hearing impaired.
References
Publications (0)
Data not yet available
No reference posted for this study.