Clinical trial · Observational
A Nomogram Model to Predict Central Lymphnode Metastasis in Thyroid Papillary Carcinoma
A Nomogram Model to Predict Central Lymphnode Metastasis in Thyroid Papillary Carcinoma Suitable for Primary Hospitals
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
To establish and validate a suitable and practical nomogram for primary hospitals to predict the risk of central lymph node metastasis (CLNM) among thyroid papillary carcinoma (PTC) patients based on clinical and ultrasound characteristics among Chinese population，1000 PTC patients were retrospectively reviewed who underwent bilateral thyroidectomy or lobectomy plus central lymph node dissection（CLND） between June 2014 and September 2019 in Sun Yat-sen Memorial Hospital (Guangzhou, South China), and then LASSO regression analysis was performed to screen out the possible predictors. Another 200 PTC patients from the First Affiliated Hospital of Zhengzhou University (Zhengzhou, North China) who underwent bilateral thyroidectomy or lobectomy plus CLND between March 2019 and November 2020 were enrolled to construct the nomogram. The area under the receiver operating characteristic (ROC) curves (AUC), calibration curves and decision curve analysis (DCA) were used to evaluate the nomogram.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Thyroid Papillary Carcinoma | Thyroid Gland Papillary Carcinoma | ALIAS | 0.90 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| male | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- label
- female group
- description
- all are female
- label
- male group
- description
- all are male
- interventionNames
- Other: male
Primary outcomes (1)
- measure
- Multivariate logistic regression analysis
- timeFrame
- 1day
- description
- Multivariate logistic regression analysis were conducted to determine the potential nonlinear association between predictors and and the risk of CLNM.
Eligibility
Eligibility (as posted)
- Sex
- All
Show eligibility criteria text
Inclusion Criteria: * underwent TC operation for the first time * confirmed as PTC by postoperative pathological examination * underwent ipsilateral or bilateral CLND Exclusion Criteria: * complicated with other subtypes of TC or thyroid metastatic cancer * received preoperative interventional therapy (such as radiofrequency and microwave therapy) or head and neck radiotherapy
References
Publications (0)
Data not yet available