Clinical trial · Observational
Pancreaticogastrostomy Versus Pancreaticojejunostomy With Dunking Technique After Pancreaticodudenectomy: A Prospective Randomized Comparative Study
NCT05171361CI-TRIAL-00055687unknownClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
To compare between the outcomes of pancreaticogastrostomy and pancreaticojejunostomy with dunking technique after Pancreaticodudenectomy in the treatment of operable periampullary malignancies.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Pancreaticobiliary Cancer | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Pancreaticogastrostomy versus Pancreaticojejunostomy with Dunking Technique | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- label
- Pancreaticojejunostomy
- description
- With Dunking Technique after Pancreaticodudenectomy
- interventionNames
- Procedure: Pancreaticogastrostomy versus Pancreaticojejunostomy with Dunking Technique
- label
- Pancreaticogastrostomy
- description
- With Dunking Technique after Pancreaticodudenectomy
- interventionNames
- Procedure: Pancreaticogastrostomy versus Pancreaticojejunostomy with Dunking Technique
Primary outcomes (1)
- measure
- Rate of postoperative anastomosis leakage
- timeFrame
- One month
- description
- Compare between dunking in pancreaticogastrostomy and pancreaticojejunostomy and the rate of postoperative anastomosis leakage
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 75 Years
Show eligibility criteria text
Inclusion Criteria: * All cases of resectable periampullary carcinomas (cancer head of pancreas, ampullary carcinoma, distal cholangiocarcinoma and second part of duodenum adenocarcinoma) that are surgically fit according to ASA. Exclusion Criteria: * 1\. Surgically unfit cases according to ASA 2. Locally advanced irresectable cases * Abutment or encasement of coeliac trunk * Encasement of SMA less than 180 degree of its axis * Encasement of portal/SMV more than 180 degree of its axis or infiltration segment too long more than 2.5 cm that the remaining segment will not coapts after resection. 3\. Metastatic disease
References
Publications (2)
- BACKGROUNDCheng Y, Briarava M, Lai M, Wang X, Tu B, Cheng N, Gong J, Yuan Y, Pilati P, Mocellin S. Pancreaticojejunostomy versus pancreaticogastrostomy reconstruction for the prevention of postoperative pancreatic fistula following pancreaticoduodenectomy. Cochrane Database Syst Rev. 2017 Sep 12;9(9):CD012257. doi: 10.1002/14651858.CD012257.pub2. PMID 28898386
- BACKGROUNDQue W, Fang H, Yan B, Li J, Guo W, Zhai W, Zhang S. Pancreaticogastrostomy versus pancreaticojejunostomy after pancreaticoduodenectomy: a meta-analysis of randomized controlled trials. Am J Surg. 2015 Jun;209(6):1074-82. doi: 10.1016/j.amjsurg.2014.07.019. Epub 2015 Jan 22. PMID 25743406