Clinical trial · Interventional
Autologous Patch Healing vs. Secondary Intention Healing After Mohs Micrographic Surgery
Autologous Patch Healing vs. Secondary Intention Healing After Mohs Micrographic Surgery - A Randomized Controlled Trial
NCT05170035CI-TRIAL-00064775unknownN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The primary objects of this study is to explore the potential effect of the autologous patch to optimize wound healing after skin cancer surgery with Mohs micrographic surgery (MMS) in the face in a randomized controlled trial comparing autologous patch healing versus secondary intention healing.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Basal Cell Carcinoma | Basal Cell Carcinoma | ONTOLOGY_EXACT | 0.90 |
| Skin Cancer | Malignant Skin Neoplasm | ALIAS | 0.90 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| MMS and secondary intention healing | Procedure | — | UNRESOLVED |
| MMS + Autologous patch | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- MMS + Autologous patch
- description
- Mohs micrographic surgery + Autologus patch formed from 18 ml venous blood sample collected from the patient + polymycin-terramycin B ointment and a Jelonet applied on top of the patch.
- interventionNames
- Procedure: MMS + Autologous patch
- type
- ACTIVE_COMPARATOR
- label
- MMS + Secondary intention healing
- description
- Mohs micropgraphic surgery + Polymycin-terramycin B ointment + dry wound dressing
- interventionNames
- Procedure: MMS and secondary intention healing
Primary outcomes (1)
- measure
- Blinded assesment of wound healing at day 18-20.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 100 Years
Show eligibility criteria text
Inclusion Criteria: 1. Subjects undergoing MMS for biopsy verified primary nodular basal cell carcinoma in the face, head and neck area on a location suitable for secondary intention healing and thus may also be suitable for autologous patch healing 2. Presenting relevant medical record report at study initiation 3. Written informed consent obtained from subject 4. Understanding of investigation procedures and willingness to abide to all procedures during the course of the investigation. Exclusion Criteria: 1. A subjects with major systemic disease not yet stabilized 2. Significant history or current evidence of a medical, psychological or other disorder that, in the investigator's opinion, would preclude enrollment into the study. 3. Pregnant or breast feeding 4. Unable to follow the outlined study protocol 5. Participation in other studies at the same time that may affect the wound healing.
References
Publications (0)
Data not yet available
No reference posted for this study.