Clinical trial · Interventional
Consequences of Eccentric Cycling on Exercise-related Neuromuscular Responses and Biomarkers in Breast Cancer Patients
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This is a monocentric, prospective and interventional study aimed to investigating the physiological responses of eccentric compared to concentric cycling realized 1) at the same metabolic demand and 2) at the same mechanical power output. In order to compare the physiological responses between these two cycling modalities, 3 cycling sessions should be performed for each patient where concentric one will serve as reference / comparison to the eccentric one: * Session (a): eccentric cycling * Session (b): high intensity concentric cycling realized at the same mechanical power output than eccentric cycling * Session (c): low intensity concentric cycling realized at the same metabolic demand than eccentric cycling The 3 sessions will be performed for each patient and order will be randomized.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Breast Cancer | Malignant Breast Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (3)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Session (a) | Other | — | UNRESOLVED |
| Session (b) | Other | — | UNRESOLVED |
| Session (c) | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- EXPERIMENTAL
- label
- eccentric cycling compared to concentric cycling
- description
- Every participant will perform the same protocol and will participated to the 3 experimental sessions (a, b and c) of the assigned intervention.
- interventionNames
- Other: Session (a)
- Other: Session (b)
- Other: Session (c)
Primary outcomes (1)
- measure
- Investigate the physiological responses of the eccentric cycling on the knee extensors muscles by changes of neuromuscular parameters
- timeFrame
- 24 hours after pedaling sessions
- description
- Measurement of neuromuscular fatigue via change in maximal voluntary isometric contraction of the knee extensors muscles registered via a force sensor.
Secondary outcomes (8)
- measure
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Woman who completed (neo)adjuvant chemotherapy since less than 1 year for a breast cancer * Woman under hormonotherapy, or menopausal woman, or woman in amenorrhea Exclusion Criteria: * Pregnant and nursing woman * psychiatric, musculoskeletal or neurological disorders * presenting at least one contraindication to the use of the transcranial magnetic stimulation * presenting at least one contraindication to the realisation of the maximum effort test
References
Publications (0)
Data not yet available