SP Thoracic IDE Study

Inclusion Criteria:

* Age \> 21 years
* BMI ≤ 35
* ASA ≤ 3
* Willing and able to provide a written informed consent
* Willing and able to comply with the study protocol requirements including follow-up examinations at 14 days and 30 days post-operatively, and post-market long term follow-up on an annual basis through 5 years

Lobectomy Inclusion Criteria:

\- Clinical stage I or II primary lung cancer or other suspected lung malignancy; or benign lung disease requiring resection; primary tumor ≤ 5cm diameter

Thymectomy Inclusion Criteria:

\- Masaoka clinical stage I or II thymoma; or thymectomy for myasthenia gravis; thymic mass ≤ 5 cm diameter

Exclusion Criteria:

* Clinical or radiological evidence of mediastinal or systemic metastatic disease
* Life expectancy \< 6 months
* Subject with a known bleeding or clotting disorder
* Subjects actively receiving therapeutic-dose anticoagulation or anti-platelet medications at the time of operation
* Uncontrolled systemic illness 6 months prior to planned surgical procedure including, but not limited to ongoing or active infection, symptomatic congestive heart failure, unstable angina pectoris, cardiac arrhythmia, or psychiatric illness/social situations that would limit compliance with study requirements
* Previous chemotherapy, immunotherapy and/or radiation therapy for treatment of the cancer to be resected
* Subject has a contraindication for general anesthesia or surgery
* Subjects under active immunomodulatory or immunosuppressive regimen (e.g. transplant patient, high-dose steroid requirement) within 30 days prior to the planned surgical procedure. For myasthenia patients, if steroids are weaned down to prednisone ≤ 5 mg/day prior to day of surgery, the patient may be enrolled
* Previous sternotomy
* Subject belongs to vulnerable population
* Subject is pregnant or suspected to be pregnant or breastfeeding

Lobectomy Exclusion Criteria:

* Tumor involving carina or any airway requiring sleeve resection, bronchoplasty
* Tumor requiring resection of local structures (e.g. chest wall) or extended resection such as bilobectomy
* History of pulmonary hypertension
* Previous ipsilateral thoracic surgery or radiotherapy

Thymectomy Exclusion Criteria:

* Uncontrolled myasthenia gravis symptoms at the time of scheduled surgery
* Tumor requiring resection of local structures (except pericardium)
* Confirmed thymic carcinoma

Intraoperative Exclusion Criteria:

\- Anatomy determined intra-operatively to be unsuitable for minimally invasive surgery