Clinical trial · Interventional
Endocuff With or Without AI-assisted Colonoscopy
Endocuff With or Without Artificial Intelligence-assisted Colonoscopy in Detection of Colorectal Adenoma: a Randomized Colonoscopy Trial
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Colonoscopy is considered the gold standard for diagnosis of colonic polyps. However, it was reported that colonoscopy could still miss colonic polyps. Many attempts have been made to improve the detection rate of colonoscopy. Artificial intelligence (AI) is a promising new technique to improve detection rate of colonic adenoma. However, it remains uncertain whether whether the combined use of Endocuff and AI assisted examination could help to further improve the adenoma detection rate. This is a prospective randomized trial comparing the use of endocuff with AI, AI alone or conventional colonoscopy examination on adenoma detection rate.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Colonic Adenoma | Colon Adenoma | ALIAS | 0.90 |
| Colonic Cancer | — | UNRESOLVED | — |
| Colonic Polyp | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| AI alone | Device | — | UNRESOLVED |
| Endocuff with AI | Device | — | UNRESOLVED |
Design
Arms and outcomes
Arms (3)
- type
- ACTIVE_COMPARATOR
- label
- Endocuff- AI assisted colonoscopy
- description
- Endocuff (Olympus, Hong Kong) and AI assisted colonoscopy will be used
- interventionNames
- Device: Endocuff with AI
- type
- ACTIVE_COMPARATOR
- label
- AI-assisted colonoscopy
- description
- AI assisted colonoscopy will be used
- interventionNames
- Device: AI alone
- type
- NO_INTERVENTION
- label
- Conventional colonoscopy
- description
- Conventional colonoscopy will be used without AI or Endocuff.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 40 Years
Show eligibility criteria text
Inclusion Criteria: * All adult patients, aged 40 or above, undergoing outpatient colonoscopy in the Queen Mary Hospital, Tung Wah Hospital and Tuen Mun Hospital in Hong Kong will be recruited. Exclusion Criteria: * Patients will be excluded if they have history of inflammatory bowel disease, colorectal cancer, previous bowel resection, Peutz-Jeghers syndrome, familial adenomatous polyposis or other polyposis syndromes, bleeding tendency or severe comorbid illnesses for which polypectomy is considered unsafe. Moreover, after randomization, if the cecum could not be intubated for various reasons or Boston Bowel Preparation Scale (BBPS) score is \<2, these patients will be excluded
References
Publications (1)
- DERIVEDLui TK, Lam CP, To EW, Ko MK, Tsui VWM, Liu KS, Hui CK, Cheung MK, Mak LL, Hui RW, Wong SY, Seto WK, Leung WK. Endocuff With or Without Artificial Intelligence-Assisted Colonoscopy in Detection of Colorectal Adenoma: A Randomized Colonoscopy Trial. Am J Gastroenterol. 2024 Jul 1;119(7):1318-1325. doi: 10.14309/ajg.0000000000002684. Epub 2024 Feb 2. PMID 38305278