Clinical trial · Observational
Towards A Better Paradigm for Head and Neck Cancer Treatment Applying Artificial Intelligence. HNC-TACTIC.
Towards A Better Paradigm for Head and Neck Cancer Treatment Applying Artificial Intelligence: an International Cohort Study of Electronic Health Records. HNC-TACTIC.
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This will be an international, multicenter, retrospective, observational, and data-driven study using secondary data captured in EHRs. The extraction of the data captured in the EHRs will be performed with SAVANA's EHRead®, an innovative data-driven system based on Natural Language Processing (NLP) and machine learning. For all patients, the Index Date is defined as the timepoint within the study period when they fulfill ALL inclusion criteria and no exclusion criteria. Follow-up comprises the period between Index Date and the last EHR available within the study period. Additional variable-specific time windows may be considered to optimize data collection.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Head and Neck Cancer | Malignant Head and Neck Neoplasm | ALIAS | 0.90 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| No intervention - Just description and predictive models | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (3)
- label
- Patients with all stages of HNSCC (Full analysis set)
- description
- To describe median OS by primary tumor location (oral cavity, oropharynx, larynx, and hypopharynx) in HNSCC patients after stratification for prognostic factors, including tumor stage and treatment.
- interventionNames
- Other: No intervention - Just description and predictive models
- label
- Patients with early and locally advanced stages
- description
- To describe clinical characteristics and treatments and to compare OS in locally advanced HNSCC patients
- interventionNames
- Other: No intervention - Just description and predictive models
- label
- Patients with recurrent or metastatic disease
- description
- To describe the epidemiologic and clinical characteristics, and treatment and the impact of introducing immunotherapy in recurrent or metastatic HNSCC
- interventionNames
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Patients ≥18 years old. * Patients diagnosed with HNSCC * For selected exploratory analyses, patients diagnosed with nasopharynx, paranasal sinus, and salivary gland tumors. Exclusion Criteria: * Patients with follow-up of less than 6 months, except if deceased (any cause) in the 6 months after HNSCC diagnosis
References
Publications (0)
Data not yet available