Clinical trial · Interventional
Effects of a Manual Therapy Program to Reduce the Evolution Time of Axillary Web Syndrome
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
ABSTRACT Breast cancer is the most common malignant tumor in women, with more than a million new cases annually. One of the most frequent surgical and post-actinic sequelae and well known is postmastectomy lymphedema. The axillary web syndrome is another sequel that limits the functionality of the patient and delays the protocol times of application of treatments cancer, and in many cases this sequela is misdiagnosed. This surgical sequelusually disappears spontaneously after the third month of appearance, but this implies a long period of discomfort and limitations for the user, at the same time that it may delay the application of Radiotherapy within the indicated protocol deadlines (due to the need for a body posture with abduction and flexion of the affected upper limb for its application and with the lymphatic thrombus is impossible to get). With the present quasi-experimental study, the investigator intend to show that the application of Kinesitherapy and stretching from the beginning of the appearance of the cord, in a controlled and scheduled way by the physiotherapist, it is possible to reduce the time in which the lymphatic thrombus is present, and therefore, recover functionality, mobility, reduce pain and be able to apply the patients´ treatments within of the established deadlines. The investigator intend to apply this therapy in the intervention group and compare thrombus evolution times with the control group.
Conditions
Conditions (6)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Breast Cancer | Malignant Breast Neoplasm | CURATED_EXACT | 0.92 |
| Mastectomy; Lymphedema | — | UNRESOLVED | — |
| Movement Disorders | — | UNRESOLVED | — |
| Shoulder Syndrome | — | UNRESOLVED | — |
| Thrombi | — | UNRESOLVED | — |
| Thrombosis | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Kinesiotherapy, Physiotherapy, Health Education | Other | — | UNRESOLVED |
| Manual Therapy, Physiotherapy, Kinesiology, Scar Massage | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Patients with Axilliary Web Syndrome and manual therapy and scar massage.
- description
- These users will come from the first moment of the diagnosis of the thrombus in our unit, to receive manual therapy by the physical therapist. They will receive 15 sessions of manual therapy by the physiotherapist, 5 days a week, each session being approximately 40 minutes long. The session will begin with pendulum exercises of the shoulder to warm up the joint and give proprioceptive stimulation to the joint capsule. The physiotherapist will perform passive stretches looking to put tension on the cord lymphatic, never exceeding grade 6 VAS pain. Mainly the shoulder will be worked affected, and if the cord reaches the crease of the elbow or thumb, the extension-supination of the elbow, and ulnar deviation of the wrist. Scar massage will be done in the area where the lymphatic cord originates at the proximal level while maintaining the tolerable tension of the lymphatic cord (during the massage also pain grade 6 VAS will be exceeded).
- interventionNames
- Other: Manual Therapy, Physiotherapy, Kinesiology, Scar Massage
- type
- OTHER
- label
- Patients with Axilliary Web Syndrome and health education and kinesiotherapy.
- description
- These users will be instructed in hygienic-postural care and active auto-kinesitherapy assisted to perform daily for 30 minutes. The investigators will value following the instructions every 30 days
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Patient over 18 years old. * Mastectomized patients (either radical or conservative surgery). * Patient with lymphatic thrombus in the upper limb ipsilateral to the surgical intervention. Exclusion Criteria: * Significant psychological alterations that would prevent the retrieval of the information necessary for the investigation. * Significant neurological alterations that would prevent the retrieval of the information necessary for the investigation. * Patients in a situation of legal dispute that would affect their intervention in this study. * Metastasis not treated with chemotherapy treatment.
References
Publications (32)
- RESULTSancho-Garnier H, Colonna M. [Breast cancer epidemiology]. Presse Med. 2019 Oct;48(10):1076-1084. doi: 10.1016/j.lpm.2019.09.022. Epub 2019 Nov 6. French. PMID 31706896
- RESULTWaks AG, Winer EP. Breast Cancer Treatment: A Review. JAMA. 2019 Jan 22;321(3):288-300. doi: 10.1001/jama.2018.19323. PMID 30667505
- RESULTGillespie TC, Sayegh HE, Brunelle CL, Daniell KM, Taghian AG. Breast cancer-related lymphedema: risk factors, precautionary measures, and treatments. Gland Surg. 2018 Aug;7(4):379-403. doi: 10.21037/gs.2017.11.04. PMID 30175055
- RESULTShao Y, Zhong DS. Manual lymphatic drainage for breast cancer-related lymphoedema. Eur J Cancer Care (Engl). 2017 Sep;26(5). doi: 10.1111/ecc.12517. Epub 2016 May 11. PMID 27167238
- RESULTSoriano-Maldonado A, Carrera-Ruiz A, Diez-Fernandez DM, Esteban-Simon A, Maldonado-Quesada M, Moreno-Poza N, Garcia-Martinez MDM, Alcaraz-Garcia C, Vazquez-Sousa R, Moreno-Martos H, Toro-de-Federico A, Hachem-Salas N, Artes-Rodriguez E, Rodriguez-Perez MA, Casimiro-Andujar AJ. Effects of a 12-week resistance and aerobic exercise program on muscular strength and quality of life in breast cancer survivors: Study protocol for the EFICAN randomized controlled trial. Medicine (Baltimore). 2019 Nov;98(44):e17625. doi: 10.1097/MD.0000000000017625. PMID 31689771
- RESULTTastaban E, Soyder A, Aydin E, Sendur OF, Turan Y, Ture M, Bilgen M. Role of intermittent pneumatic compression in the treatment of breast cancer-related lymphoedema: a randomized controlled trial. Clin Rehabil. 2020 Feb;34(2):220-228. doi: 10.1177/0269215519888792. Epub 2019 Dec 4. PMID 31795748
- RESULTYeung WM, McPhail SM, Kuys SS. A systematic review of axillary web syndrome (AWS). J Cancer Surviv. 2015 Dec;9(4):576-98. doi: 10.1007/s11764-015-0435-1. Epub 2015 Feb 15.