Clinical trial · Observational
Change of Circulating Tumor Cells During Laparoscopic or Transanal Endoscopic Surgery for Rectal Cancer.
Sixth Affiliated Hospital, Sun Yat-sen University
NCT05109130CI-TRIAL-00065611unknownClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The primary purpose of this study is to compare the changes of circulating tumor cells (CTCs) at different time points in rectal cancer patients undergoing laparoscopic or transanal endoscopic radical resection. Our secondary purpose is to explore the effects of perioperative circulating tumor cells on tumor recurrence and metastasis.
Conditions
Conditions (4)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Laparoscopic Surgery | — | UNRESOLVED | — |
| Neoplastic Cells, Circulating | — | UNRESOLVED | — |
| Rectal Neoplasms | Rectal Neoplasm | ONTOLOGY_EXACT | 0.98 |
| Transanal Endoscopic Surgery | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Surgical approach | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- label
- laparoscopic surgery
- description
- Laparoscopic total mesorectal excision was performed on the enrolled patients.
- interventionNames
- Procedure: Surgical approach
- label
- Transanal endoscopic surgery
- description
- Transanal total mesorectal excision was performed on the enrolled patients.
- interventionNames
- Procedure: Surgical approach
Primary outcomes (1)
- measure
- Change of circulating tumor cells during laparoscopic or transanal endoscopic surgery
- timeFrame
- 1 years
- description
- To determine the changes of circulating tumor cells in rectal cancer patients undergoing laparoscopic or transanal endoscopic radical resection before operation and 5 days after operation.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: 1. Mid-low rectal cancer. 2. Single lesion. 3. No metastasis. 4. Clinical Stage T2-3, N0-1. Exclusion Criteria: 1. History of malignant tumors. 2. Acute bowel obstruction, bleeding or perforation. 3. Received neoadjuvant treatment. 4. Tumor over 6cm in diameter or in severe adhesion with surrounded tissues. 5. Severe other contradictions of surgery. 6. Pregnant women will be excluded. Exit Criteria: 1. The patient suffered from massive hemorrhage. 2. The operation mode needs to be changed according to the patient's condition.
References
Publications (0)
Data not yet available
No reference posted for this study.