Clinical trial · Observational
The Cardiac Stress and Electrocardiographic Changes Caused by Lung Cancer Surgery
The Cardiac Stress and Electrocardiographic Changes Caused by Lung Cancer Surgery.
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Lung cancer surgery causes significant changes in the small circulation as well as changes in the intrathoracic anatomy. The effects of lung cancer surgery on electrocardiography and the cardiac stress associated with the procedures have not been previously extensively studied. The aim of the present study is to ascertain whether modern mini-invasive lung cancer surgery causes changes in the electrocardiogram, and whether these changes are transitory during short-term follow-up. Furthermore, the study aims to describe whether lung cancer surgery causes significant cardiac stress detectable by intraoperative electrocardiography.
Conditions
Conditions (4)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Arrhythmia | — | UNRESOLVED | — |
| Lung Cancer | Malignant Lung Neoplasm | CURATED_EXACT | 0.92 |
| Myocardial Ischemia | — | UNRESOLVED | — |
| Surgery | — | UNRESOLVED | — |
Interventions
Interventions (0)
Data not yet available
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (13)
- measure
- Postoperative electrocardiographic p-, R-, and T-wave amplitude changes
- timeFrame
- 2 weeks
- description
- Amplitude changes in the 12-lead rest electrocardiography in millimeters, analyzed daily postoperatively.
- measure
- Postoperative QRS-duration
- timeFrame
- 2 weeks
- description
- The duration of the QRS-complex in milliseconds in the electrocardiogram, measured daily postoperatively using 12-lead rest electrocardiogram.
- measure
- Postoperative PQ-delay
- timeFrame
- 2 weeks
- description
- Changes in the PQ-delay in milliseconds in the 12-lead rest electrocardiogram measured daily postoperatively.
- measure
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Adult patients scheduled for elective lung cancer surgery * Willing to participate in the study * Curatively aimed surgery * Preoperative decision for mini-invasive surgery Exclusion Criteria: * Participation in any other clinical trial * Previous chronic or paroxysmal atrial fibrillation or atrial flutter * Cardiac pacemaker * History of cardiac conduction disturbances including bundle branch blocks * History of cardiac ablation procedures * History of previous surgery in the thoracic area including open heart surgery * Preoperatively anticipated need for concomitant thoracic wall resection * Preoperatively anticipated need for open surgery
References
Publications (0)
Data not yet available