Clinical trial · Observational
The Role of Genetic Factors in the Development of Breast Cancer in the Kazakh Population
Preventive and Personalized Medicine (2021-2023)
NCT05090605CI-TRIAL-00064667completedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This is a GWAS study that aims to identify possible candidate genes associate to breast cancer by exploring single nucleotide polymorphism (SNP) in a group of breast cancer, in the Kazakh population. The investigators hypothesize that the careful phenotyping of the subject sand matching with increase the power to find SNP significantly associate with breast cancer
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Breast Cancer | Malignant Breast Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| DNA analysis | Genetic | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- label
- Experimental group:
- description
- Patients with breast cancer
- interventionNames
- Genetic: DNA analysis
- label
- Control group
- description
- Patients without breast cancer
- interventionNames
- Genetic: DNA analysis
Primary outcomes (1)
- measure
- number of SNPs associated with breast cancer
- timeFrame
- 1 year
- description
- Using GWAS to identify candidate genes associate with breast cancer
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
- Maximum age
- 60 Years
Show eligibility criteria text
Inclusion Criteria: * Persons with a histologically confirmed diagnosis of breast cancer. * The age of patients is from 18 to 60 years; * Persons of Kazakh nationality, whose paternal and maternal grandparents are Kazakhs. * Persons who are able and willing to provide written informed consent; * Persons capable and willing to comply with the research protocol; Exclusion Criteria: * Persons under 18 and over 60 years old; * Persons who, in the opinion of the researcher, are mentally or legally incapacitated, which prevents obtaining informed consent; * Pregnant or lactating women; * Tuberculosis of any localization in the active phase and in history; * Severe and decompensated diseases of the liver and kidneys, cardiovascular system; * Severe and decompensated course of endocrine diseases; * Lack of histological verification of breast tumor
References
Publications (0)
Data not yet available
No reference posted for this study.