Clinical trial · Interventional
Comparison Between Two Different Doses of Nulbuphine _bupivacaine in TAP Block in Cancer Abdominal Surgeries
Nalgesic Effect of Nulbuphine-bupivacaine Combination in Ultrasound Guided Transversus Abdominis Plane Block in Patients Undergoing Major Abdominal Cancer Surgeries .
NCT05090579CI-TRIAL-00054649unknownN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
To compare the analgesic effect of two different doses of nulbuphine (10 mg and 20 mg) added to bupivacaine in bilateral subcostal single injection in ultrasound-guided TAP block for abdominal surgeries.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Pain, Postoperative | — | UNRESOLVED | — |
Interventions
Interventions (3)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Active Comparator:Group ll (BN20) | Procedure | — | UNRESOLVED |
| Active Comparator:Group lll (B) | Procedure | — | UNRESOLVED |
| Group I (BN10) | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (3)
- type
- ACTIVE_COMPARATOR
- label
- Group I (BN10)
- description
- patients will receive an ultrasound-guided TAP block with 20 mL of 0.25% bupivacaine , 1 mL of 10 mg of nulbuphine plus 4 mL of normal saline to reach 25 mL as total volume on each side of the abdominal wall.
- interventionNames
- Procedure: Group I (BN10)
- type
- ACTIVE_COMPARATOR
- label
- Group II (BN20)
- description
- patients will receive an ultrasound-guided TAP block with 20 mL of 0.25% bupivacaine ,2 mL of 20 mg of nulbuphine plus 3 mL of normal saline to reach 25 mL as total volume on each side of the abdominal wall.
- interventionNames
- Procedure: Active Comparator:Group ll (BN20)
- type
- ACTIVE_COMPARATOR
- label
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria:- * ASA classification I-ll, * Aged \>18 years, * weight 50-85 kg, * Patients who will undergo abdominal cancer surgery. Exclusion Criteria:- * Patient's refusal, * patients with a history of allergies to studied drugs, * Patients with coagulation disorders, * Patients with opioid dependence, * Patients with morbid obesity (body mass index more than 40 kg/m2), * Patients with sepsis, * patients with psychiatric illnesses that will interfere with the perception and assessment of pain .
References
Publications (0)
Data not yet available
No reference posted for this study.