Clinical trial · Observational
Perineal Flap Reconstruction Following Surgery for Advanced Pelvic Malignancy
PelvEx 8: Perineal Flap Reconstruction Following Surgery for Advanced Pelvic Malignancy
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Flap reconstruction is utilised increasingly for repair of skin and soft tissue defects following pelvic exenteration. Many methods have been proposed but the outcomes associated with each remain largely unknown and the choice dependant on surgeon preference and patient/ disease characteristics. This review sought to assess the preferred methods for perineal reconstruction following pelvic exenteration by retrospectively assessing the outcomes associated with each at an international, multi-centre level.
Conditions
Conditions (6)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Flap Disorder | — | UNRESOLVED | — |
| Flap Ischemia | — | UNRESOLVED | — |
| Flap Necrosis | — | UNRESOLVED | — |
| Pelvic Cancer | Malignant Pelvic Neoplasm | ALIAS | 0.90 |
| Perioperative Complication | — | UNRESOLVED | — |
| Rectal Cancer | Malignant Rectal Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Flap reconstruction | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- Flap reconstruction
- description
- Patients who had a flap formation as part of a multi-visceral extended resection for advanced pelvic (rectal, urological, gynaecological, sarcomatous origin) malignancy
- interventionNames
- Procedure: Flap reconstruction
Primary outcomes (4)
- measure
- Flap reconstruction by procedure
- timeFrame
- July 2016 - July 2021
- description
- Type of flap formation
- measure
- Morbidity
- timeFrame
- July 2016 - July 2021
- description
- Short-term (\<30 days) outcomes associated with each type
- measure
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Histologically proven locally advanced or recurrent pelvic cancer (all subtypes - Rectal, Urological, Gynaecological, Sarcoma) * Aged over 18 years * Undergoing a multi-visceral extended pelvic resection and requiring reconstruction of a skin and soft tissue defect as a result * Time period: 1st July 2016 - 1st July 2021 Exclusion Criteria: * Strong evidence of metastatic or peritoneal disease * No immediate flap reconstruction performed at time of extended pelvic resection/pelvic exenteration, or flap reconstruction performed as a delayed procedure or as a response to a complication of prior pelvic exenteration * Insufficient patient follow-up (Minimum of 30 days)
References
Publications (0)
Data not yet available