Clinical trial · Observational
Routine Transcervical Thymectomy in MEN-1 Patients
Revisiting the Evidence for Routine Transcervical Thymectomy for the Prevention of Thymic Carcinoid Tumours in MEN-1 Patients a Case Series
NCT05061784CI-TRIAL-00054193completedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
A case series was built after review of available literature by searching four databases (PubMed, Embase, Medline and Cochrane Library) for observational studies or case reports on routine prophylactic TCT for MEN-1 and the development of thymic carcinoids.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Multiple Endocrine Neoplasia Type 1 (MEN-1) | Multiple Endocrine Neoplasia Type 1 | ONTOLOGY_EXACT | 0.85 |
| Thymic Carcinoid | Thymus Neuroendocrine Tumor | ALIAS | 0.90 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Routine thymectomy, which has been performed | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- MEN-1 patients who underwent routine thymectomy during parathyroidecotmy
- description
- A case series was built after review of available literature by searching four databases (PubMed, Embase, Medline and Cochrane Library) for observational studies or case reports on routine prophylactic TCT for MEN-1 and the development of thymic carcinoids.
- interventionNames
- Procedure: Routine thymectomy, which has been performed
Primary outcomes (1)
- measure
- Incidence of thyme carcinoid
- timeFrame
- The timeframe will be from date of transcervical thymectomy until the date of documented diagnosis of diagnosis of thymic NET; progression of disease or date of death from any cause, whichever came first, assessed up to 100 months.
- description
- Retrospective review of published studies
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Studies including MEN-1 patients who underwent a routine thymectomy during parathyoidectomy * We accepted randomized controlled trials or observational studies that included patients of any age who underwent a routine TCT in the setting for MEN-1, published as full-length articles in peer-reviewed journals, which mentioned data on thymic carcinoid tumours. Exclusion Criteria: * We excluded reviews, letters, conference proceedings and non-English publications.
References
Publications (0)
Data not yet available
No reference posted for this study.