Clinical trial · Observational
Resection Margin of Transverse Colon Cancer With Extracorporeal Versus Intracorporeal Anastomosis
The Impact of Intracorporeal Anastomosis on Resection Margin During Laparoscopic Radical Resection of Transverse Colon Cancer: a Retrospective Multi-center Study
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The approach of anastomosis in laparoscopic resection of transverse colon cancer (TCC) has rarely been discussed. This study aims to compare the resection margin of TCC with extracorporeal anastomosis (ECA) versus intracorporeal anastomosis (ICA). Patients who underwent laparoscopic resection of TCC from August 2019 to July 2021 in 13 participating centers are included in this study. According to the approach of anastomosis, patients are divided into two groups, ECA group and ICA group respectively. The clinical characteristics, the perioperative outcomes and the pathological results (especially the length of resection margin) are compared between the two groups. The length of two-sided resection margins (long margin, short margin) are measured on formalin-fixed specimens and those with short margin less than 4.0 cm are defined as unqualified specimens.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Transverse Colon Cancer | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| approach of anastomosis | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- label
- ECA group
- description
- TCC with extracorporeal anastomosis (ECA)
- interventionNames
- Procedure: approach of anastomosis
- label
- ICA group
- description
- TCC with intracorporeal anastomosis (ICA).
- interventionNames
- Procedure: approach of anastomosis
Primary outcomes (1)
- measure
- length of the resection margin
- timeFrame
- one month after surgery
- description
- length of the two -sided resection margins measured on formalin-fixed specimen (CM)
Eligibility
Eligibility (as posted)
- Sex
- All
Show eligibility criteria text
Inclusion Criteria: * 1\. pathologically confirmed adenocarcinoma of colon * 2\. The tumor is located in the transverse colon (including hepatic or splenic flexure); * 3\. One of the following procedures was performed: transverse colectomy, right hemicolectomy, enlarged right hemicolectomy, left colectomy, enlarged left colectomy; * 4\. Laparoscopic surgery (laparoscopy-assisted surgery or complete laparoscopic surgery) from August 2019 to July 2021; * 5\. Radical resection (R0) was accomplished; Exclusion Criteria: * 1\. Simultaneous multiple colorectal cancer; * 2\. history of colorectal surgery (except endoscopic surgery); * 3\. robot-assisted surgery; * 4\. palliative resection (non-R0 resection) or palliative bypass; * 5\. the approach of anastomosis could not be determined from the documents; * 6\. the length of resection margin was not recorded in pathological report;
References
Publications (1)
- DERIVEDZhong H, Cai Z, Lu J, Yang Y, Xu Q, Wang N, He L, Hu X, Fingerhut A, Zheng M, Lu A, Liu Z, Xiao Y, Feng B. Pathological and perioperative outcomes of extracorporeal versus intracorporeal anastomosis in laparoscopic transverse colon cancer resection: retrospective multicentre study. BJS Open. 2023 May 5;7(3):zrad045. doi: 10.1093/bjsopen/zrad045. PMID 37161672