Clinical trial · Observational
Transcriptomic Study of IBD-associated Colorectal Cancer
Transcriptiomic Analysis of Inflammatory Bowel Disease-associated Colorectal Cancer. A French Retrospective Study of 26 Cases Identified at the Nancy University Hospital
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Chronic inflammatory bowel disease (IBD) is associated with an increased risk of colorectal cancer (CRC) in historical cohorts. The pathways of oncogenesis of these CRCs, which are very different clinically from de novo CRCs, are currently unknown. The aim of our work is to identify specific molecular signatures of CRC occurring in the setting of IBD.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Colorectal Cancer, Genetics of | Malignant Colorectal Neoplasm | CURATED_BROADER | 0.80 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| transcriptomic analysis | Genetic | — | UNRESOLVED |
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (1)
- measure
- IBD associated CRC oncogenesis
- timeFrame
- 1 year
- description
- Percentage of gene expression variation in CRC tumor tissue samples in the following groups patients with CRC and IBD
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 100 Years
Show eligibility criteria text
Inclusion Criteria: * Person 18 years of age or older * Person with colorectal cancer in the context of IBD * Person who has received complete information on the organization of the research and who has signed an informed consent * Person affiliated to a social security plan or beneficiary of such a plan. Exclusion Criteria: * Person referred to in articles L. 1121-5, L. 1121-7 and L1121-8 of the public health code: * Pregnant woman, parturient or nursing mother * Minor (not emancipated) * Adult person subject to a legal protection measure (guardianship, curatorship, safeguard of justice) * Person of legal age who is unable to express his or her consent * Person deprived of liberty by a judicial or administrative decision, persons subject to psychiatric care under articles L. 3212-1 and L. 3213-1.
References
Publications (0)
Data not yet available