Clinical trial · Observational
Quality of Life and Patient Needs in Advanced High Grade Gliomas
Quality of Life and Patient Needs in Advanced High Grade Gliomas - A Prospective Study
NCT05039346CI-TRIAL-00068773completedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
There is limited knowledge regarding the quality of life and needs of patients with advanced high grade gliomas, especially during the end of life. By doing this research, we are able to assess caregiver and patient symptoms and needs during the end of life phase of patients with brain tumors.
Conditions
Conditions (5)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Anaplastic Astrocytoma | Anaplastic Astrocytoma | CURATED_BROADER | 0.80 |
| Brain Tumor | Brain Neoplasm | ALIAS | 0.90 |
| Glioblastoma | Glioblastoma | CURATED_BROADER | 0.80 |
| Glioma | Glioma | ONTOLOGY_EXACT | 0.98 |
| Quality of Life | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Phone interviews | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- label
- Brain Tumor
- description
- Patients who are diagnosed with a high grade glioma that is progressive and therapy resistance. Patients will have a KPS of 60 or less.
- interventionNames
- Other: Phone interviews
- label
- Care Giver
- description
- Should a patient be unable to answer, the care giver will step in and provide surrogate answers. Additionally, at four weeks following the patient's death, the patient's care giver will be interviewed by utilizing a validated questionnaire.
- interventionNames
- Other: Phone interviews
Primary outcomes (2)
- measure
- Quality of life and end of life symptoms in brain tumor patients
- timeFrame
- 12 months
- description
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Age \>18 * Tissue proven diagnosis of a high grade brain tumor * Disease progression by MRI * Therapy resistant tumor to 2nd line chemotherapy * Karnofsky Performance Scale (KPS) score of 60 or less * Patient will need to assign caregiver Exclusion Criteria: * None
References
Publications (0)
Data not yet available
No reference posted for this study.