Clinical trial · Interventional
Pain After Lung Cancer Surgery - Comparing Traditional Versus Prolonged Release Nerve Blockades
Pain After Thoracoscopic Lung Surgery - the Effect of Intercostal Nerve Blockades With Standard Bupivacaine and Liposomal Bupivacaine - a Randomised Controlled Feasibility Trial
NCT05038007CI-TRIAL-00053986unknownPhase 2ClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
To investigate the effect of liposomal bupivacaine compared with bupivacaine hydrochloride for intercostal blockades for patients undergoing Video-assisted thoracoscopic surgery.
Conditions
Conditions (5)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Anesthesia, Local | — | UNRESOLVED | — |
| Blockades Neuromuscular | — | UNRESOLVED | — |
| Lung Cancer | Malignant Lung Neoplasm | CURATED_EXACT | 0.92 |
| Postoperative Pain | — | UNRESOLVED | — |
| Video Assisted Thoracoscopic Surgery | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Bupivacaine Hydrochloride | Drug | — | UNRESOLVED |
| Liposomal bupivacaine | Drug | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- ACTIVE_COMPARATOR
- label
- Control
- description
- Bupivacaine Hydrochloride in perioperative intercostal blockades
- interventionNames
- Drug: Bupivacaine Hydrochloride
- type
- EXPERIMENTAL
- label
- Intervention
- description
- Liposomal bupivacaine in perioperative intercostal blockades
- interventionNames
- Drug: Liposomal bupivacaine
Primary outcomes (1)
- measure
- Duration of analgesic effect
- timeFrame
- 48 hours
- description
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Adults independent of sex with an age of ≥ 18 years * Patients undergoing VATS as a part of either examination or treatment of lung cancer Exclusion Criteria: * Patients who are unable to understand oral and written information. * Patients with known chronic pain in the thorax which have been persisting for at least six months before the day of surgery. * Pregnant and nursing women. * Patients with hypersensitivity / allergy / Intolerance to dexamethasone or bupivacaine. * Patients receiving a planned preoperative epidural blockade during their stay. * Patients converted to open surgery.
References
Publications (0)
Data not yet available
No reference posted for this study.