Clinical trial · Interventional
Exercise Preconditioning in Ovarian Cancer
Effect of Exercise Preconditioning in Ovarian Cancer on Treatment-Related Cardiotoxicity
NCT05029154CI-TRIAL-00090950terminatedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Why stopped (as posted): Accrual not meeting pre-specified numbers.
Summary
Brief summary (as posted)
The purpose of this study is to determine if exercise preconditioning can mitigate the off target effects of chemotherapy treatment on measures of cardiovascular function, peripheral neuropathy, and quality of life.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Ovarian Cancer | Malignant Ovarian Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Attention control | Behavioral | — | UNRESOLVED |
| High intensity interval exercise | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Exercise
- description
- Patients in the exercise group will perform interval training 3 days per week.
- interventionNames
- Behavioral: High intensity interval exercise
- type
- PLACEBO_COMPARATOR
- label
- Attention Control
- description
- Physical activity education and physical activity monitoring.
- interventionNames
- Behavioral: Attention control
Primary outcomes (1)
- measure
- VO2 Peak
- timeFrame
- 22 weeks
- description
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Age 18 years or over * Presumed diagnosis of ovarian cancer and a planned chemotherapy regimen of a taxane and carboplatin with or without VEGF inhibition * Physician clearance for exercise training Exclusion Criteria: * Any patient unable/unwilling to cooperate with all study protocols * Cancer recurrence * Previous treatment with chemotherapy in the last 5-years * Medical/orthopedic co-morbidities that preclude exercise training * Significant heart, liver, kidney, blood, or respiratory disease precluding exercise participation * Peripheral vascular disease * Acute infectious disease or history of chronic infections
References
Publications (0)
Data not yet available
No reference posted for this study.