Clinical trial · Interventional
Using Technology to Optimize Collaborative Care Management of Depression in Urban and Rural Cancer Centers, SCOPE
Using Technology to Optimize Collaborative Care Management of Depression in Urban and Rural Cancer Centers (AKA: SUPPORTING COLLABORATIVE CARE TO OPTIMIZE PSYCHOSOCIAL ENGAGEMENT IN THE CANCER SETTING [SCOPE])
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Why stopped (as posted): Study closed to accrual before meeting accrual goal due to enrollment challenges and end of funding.
Summary
Brief summary (as posted)
This study compares the effectiveness of technology-enhanced collaborative care management (t-CoCM) to usual collaborative care management (u-CoCM) in achieving fidelity to processes of care and reducing depression symptoms in patients currently receiving cancer treatment. CoCM is a population-based, integrated care approach, where care managers, who are clinicians (typically clinical social workers), deliver behavioral treatments, coordinate psychosocial care, monitor outcomes, and adjust treatment with the input of a psychiatric consultant. The use of t-CoCM may improve the treatment of depression and improve patient outcomes and quality of life.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Depression | — | UNRESOLVED | — |
| Hematopoietic and Lymphoid Cell Neoplasm | Hematopoietic and Lymphoid Cell Neoplasm | ONTOLOGY_EXACT | 0.98 |
| Malignant Solid Neoplasm | Malignant Solid Neoplasm | ONTOLOGY_EXACT | 0.98 |
Interventions
Interventions (4)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Collaborative care | Other | — | UNRESOLVED |
| Interview or Focus Group | Other | — | UNRESOLVED |
| Media/technology Intervention with collaborative care | Other | — | UNRESOLVED |
| Survey Administration | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Arm I (t-CoCM)
- description
- Patients use the t-CoCM digital app platform and clinic care managers use the t-CoCM web-based registry platform to support delivery of collaborative care. Patient's complete surveys at baseline, 3, 6 and 9 months. Some patients also participate in an interview or focus group about their user experience with the t-CoCM digital platform. Care managers also participate in interviews regarding their experience with CoCM and the newly developed web-based platform.
- interventionNames
- Other: Interview or Focus Group
- Other: Media/technology Intervention with collaborative care
- Other: Survey Administration
- type
- ACTIVE_COMPARATOR
- label
- Arm II (u-CoCM)
- description
- Patients receive usual care and clinic care managers deliver usual CoCM. Patients complete surveys at baseline, 3, 6 and 9 months.
- interventionNames
- Other: Collaborative care
- Other: Survey Administration
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Patients receiving active treatment (surgery, chemotherapy, immunotherapy, targeted therapy, stem cell transplant, hormone therapy, radiation therapy) for a malignancy * \>= 18 years old * Participants must be ambulatory for clinical care visits * Clinically significant depression (Patient Health Questionnaire-9 (PHQ-9) \>= 10 with at least one cardinal symptom \> 1) * Access to smartphone, tablet, or computer with internet access; or landline * Patients who do not have a smartphone will be offered assistance in obtaining a free smartphone through the government-sponsored Lifeline Phone Program for low-resourced individuals Exclusion Criteria: * Advanced cancer or other condition that limits remaining life expectancy to less than 9 months * Already engaged in or needing immediate specialty mental health care e.g., for bipolar disorder or schizophrenia * Inability to speak and read English
References
Publications (1)
- DERIVEDFann JR, Lostutter TW, Andris L, Bates N, Rhew IC, Bauer AM, Bennett IM, Martin D, Irwin B, Powers DM, Cruz J, Hsieh G, Fogarty J. Technology-enabled collaborative care management of depression in urban and rural cancer centers: Protocol and baseline results from the SCOPE pragmatic hybrid effectiveness-implementation trial. Contemp Clin Trials. 2026 Sep;168:108409. doi: 10.1016/j.cct.2026.108409. Epub 2026 Jul 21. PMID 42480863