Clinical trial · Interventional
Comparison of Continuous ESP Versus TEA After Thoracotomy
Continuous Erector Spinae Plane Block Versus Thoracic Epidural Analgesia After Thoracotomy: A Randomized Controlled Assessor-blinded Non-inferiority Trial
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This prospective, randomized, assessor-blinded study is designed to evaluate the postoperative analgesic efficacy of the ultrasound-guided continuous erector spinae plane (ESP) block in patients undergoing thoracotomy. We hypothesize that US-guided ESP block is not inferior to thoracic epidural analgesia in terms of postoperative pain control in these patients.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Postoperative Pain | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Erector spinae plane block group | Procedure | — | UNRESOLVED |
| Thoracic epidural analgesia group | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Erector spinae plane block group (ESP group)
- description
- Patients receiving continuous unilateral ESP block. Interventions: Procedure: Ultrasound-guided unilateral ESP block via catheter placement for continuous infusion Drug: Ropivacaine 0.75% Injectable Solution Device: 21-gauge 85 mm perineural catheter, 18-gauge 100 mm stimulator needle (Silverstim, Vygon, Ecouen, France)
- interventionNames
- Procedure: Erector spinae plane block group
- type
- ACTIVE_COMPARATOR
- label
- Thoracic epidural analgesia group (TEA group)
- description
- Patients receiving thoracic epidural analgesia. Interventions: Procedure: Fluoroscopy-guided thoracic epidural analgesia Drug: Ropivacaine 0.75% Injectable Solution Device: 17-gauge Tuohy needle (FlexTip Plus®, Teleflex Medical, USA)
- interventionNames
- Procedure: Thoracic epidural analgesia group
Primary outcomes (1)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Patients scheduled to undergo elective thoracotomy for lung cancer * European Cooperative Oncology Group 0 or 1 * American Society of Anesthesiologists (ASA) physical classification I-III * Willingness and ability to sign an informed consent document Exclusion Criteria: * patients with chronic postoperative pain after thoracic surgery * patients undergoing thoracotomy with chest wall resection * allergies to anesthetic or analgesic medications * patients with coagulopathy or who continue to take anticoagulants * preoperative liver or renal dysfunction * patients with chronic pain, chronic opioid, analgesic or antidepressant or anticonvulsant use * Do not understand our study * Medical or psychological disease that can affect the treatment response
References
Publications (0)
Data not yet available