Clinical trial · Interventional
Surveillance Modified by Artificial Intelligence in Endoscopy (SMARTIE)
Multicenter Evaluation Study of the CADe System ENDOMIND in Surveillance Endoscopy for Colorectal Cancer in German Outpatient Cohort
NCT05006092CI-TRIAL-00066017SMARTIEcompletedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Evaluation of an artificial intelligence system for polyp detection (CADe)
Conditions
Conditions (4)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Artificial Intelligence | — | UNRESOLVED | — |
| CADe | — | UNRESOLVED | — |
| Polyps of Colon | — | UNRESOLVED | — |
| Surveillance Endoscopy for Colorectal Cancer | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| ENDOMIND | Device | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- surveillance endoscopy with CADe support
- description
- Endoscopy perfomed with CADe support.
- interventionNames
- Device: ENDOMIND
- type
- NO_INTERVENTION
- label
- conventional surveillance endoscopy
- description
- Endoscopy perfomed without CADe support.
Primary outcomes (1)
- measure
- adenoma detection rate
- timeFrame
- 4 months
- description
- proportion of individuals undergoing a complete screening colonoscopy who have one or more adenomas
Secondary outcomes (4)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * indication CRC surveillance endoscopy * indication post-polypectomy surveillance endoscopy * positive fecal immunochemical test in patients \>=50 years Exclusion Criteria: * reasonable suspicion of inflammatory bowl disease * reasonable suspicion of familiar polyposis Syndrome * Patient after radiation/resection of colonic parts
References
Publications (2)
- DERIVEDLux TJ, Sassmannshausen Z, Kafetzis I, Banck M, Krenzer A, Fitting D, Sudarevic B, Troya J, Boeck W, Passek F, Heubach T, Simonis B, Heil FJ, Ludwig L, Puppe F, Zoller WG, Meining A, Hann A. Artificial intelligence assisted colorectal lesion detection in private practices a randomized controlled study. NPJ Digit Med. 2026 Apr 1;9(1):284. doi: 10.1038/s41746-026-02576-8. PMID 41922731
- DERIVEDLux TJ, Banck M, Sassmannshausen Z, Troya J, Krenzer A, Fitting D, Sudarevic B, Zoller WG, Puppe F, Meining A, Hann A. Pilot study of a new freely available computer-aided polyp detection system in clinical practice. Int J Colorectal Dis. 2022 Jun;37(6):1349-1354. doi: 10.1007/s00384-022-04178-8. Epub 2022 May 11. PMID 35543874