Clinical trial · Interventional
On Dose Efficiency of Modern CT-scanners in Chest Scans
On Dose Efficiency of Modern CT-scanners in Chest Scans- a Prospective, Randomized Study
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
CT scans of the chest / thorax are of great importance both in the initial diagnosis and in the follow-up of pulmonary or thoracic diseases. As an example, CT angiography of the pulmonary arteries (CTPA) is worldwide considered to be gold standard test in patients with a suspicion for pulmonary embolism. The aim of this study is to measure and compare dose efficiency of modern CT scanners for unenhanced and contrast-enhanced scan protocols of the chest/thorax. Patients who are referred for a CT of the chest/thorax will be randomly assigned to one of the three CT scanners currently in use at our institution.
Conditions
Conditions (5)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Aortic Stenosis | — | UNRESOLVED | — |
| Lung Cancer | Malignant Lung Neoplasm | CURATED_EXACT | 0.92 |
| Pneumonia | — | UNRESOLVED | — |
| Pulmonary Disease | — | UNRESOLVED | — |
| Pulmonary Embolism | — | UNRESOLVED | — |
Interventions
Interventions (3)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| CT Scan using an Energy-Integrating Detector CT (128 slice MDCT) | Diagnostic Test | — | UNRESOLVED |
| CT Scan using an Energy-Integrating Detector CT (20-slice MDCT) | Diagnostic Test | — | UNRESOLVED |
| Imaging on Scanner with Spectral Imaging Capabilities | Diagnostic Test | — | UNRESOLVED |
Design
Arms and outcomes
Arms (3)
- type
- OTHER
- label
- Scanner 1
- description
- Imaging performed on scanner 1: Photon-Counting Detector CT
- interventionNames
- Diagnostic Test: Imaging on Scanner with Spectral Imaging Capabilities
- type
- OTHER
- label
- Scanner 2
- description
- Imaging performed on scanner 2: Energy-Integrating Detector CT (128-slice)
- interventionNames
- Diagnostic Test: CT Scan using an Energy-Integrating Detector CT (128 slice MDCT)
- type
- OTHER
- label
- Scanner 3
- description
- Imaging performed on scanner 3: Energy-Integrating Detector CT (20-slice)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria:
* patient is referred for an unenhanced CT OR contrast-enhanced CT of the chest/thorax confirmed by a board-certified radiologist ('justifying indication' according to German/European radiation protection law) AND
* patient is at least 18 years of age AND
* patient (is able to give informed consent and) has given informed consent.
Exclusion Criteria:
* high degree of medical urgency (i.e. patient cannot be consented for iv contrast according to routine procedures)
* known or suspected pregnancy, or lactating . contraindications for contrast agent (renal failure, allergy, hyperthyroidism)References
Publications (0)
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