Clinical trial · Interventional
Dose Efficiency of Modern CT Scanners in Oncologic Scans
On Dose Efficiency of Modern CT-Scanners in the Staging of Malignancies - a Prospective Randomized Study
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
CT-Staging is crucial for therapy planning of patients with malignancies. Dose efficiency and image quality are important parameters for these examinations. Up to now, scientific evidence of dose efficiency of modern CT scanners is mostly derived from retrospective analyses. This prospective study systematically analyzes dose efficiency and image quality of three modern CT scanners by randomization of patients who are scheduled for a CT scan to examine the status of malignancies. After giving informed consent and randomization (1:1:1), the CT scan will be performed at one of the modern CT scanners available at our department. This will allow a systematic allocation to the different scanners.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Metastatic Cancer | Malignant Neoplasm | CURATED_BROADER | 0.78 |
| Neoplasm Metastasis | — | UNRESOLVED | — |
| Neoplasms | Neoplasm | ONTOLOGY_EXACT | 0.90 |
Interventions
Interventions (3)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Scan at CT scanner 1 | Diagnostic Test | — | UNRESOLVED |
| Scan at CT scanner 2 | Diagnostic Test | — | UNRESOLVED |
| Scan at CT scanner 3 | Diagnostic Test | — | UNRESOLVED |
Design
Arms and outcomes
Arms (3)
- type
- OTHER
- label
- CT scanner 1
- description
- Patients will undergo imaging on scanner 1.
- interventionNames
- Diagnostic Test: Scan at CT scanner 1
- type
- OTHER
- label
- CT scanner 2
- description
- Patients will undergo imaging on scanner 2.
- interventionNames
- Diagnostic Test: Scan at CT scanner 2
- type
- OTHER
- label
- CT scanner 3
- description
- Patients will undergo imaging on scanner 3.
- interventionNames
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria:
* clinical suspicion of a malignancy or known / confirmed malignancy AND
* indication for contrast-enhanced CT of the body confirmed by board-certified radiologist ('justifying indication' according to German/European radiation protection law) AND
* patient (is able to give informed consent and) has given informed consent.
Exclusion Criteria:
* age \< 18 years
* known or suspected pregnancy
* contraindications for contrast agent (renal failure, allergy, hyperthyroidism)References
Publications (1)
- DERIVEDRisch F, Decker JA, Popp D, Sinzinger A, Braun F, Bette S, Jehs B, Haerting M, Wollny C, Scheurig-Muenkler C, Kroencke TJ, Schwarz F. Artifact Reduction From Dental Material in Photon-Counting Detector Computed Tomography Data Sets Based on High-keV Monoenergetic Imaging and Iterative Metal Artifact Reduction Reconstructions-Can We Combine the Best of Two Worlds? Invest Radiol. 2023 Sep 1;58(9):691-696. doi: 10.1097/RLI.0000000000000967. PMID 36897803