Clinical trial · Observational
Nasal Endoscopic Screening and Risk Assessment for Early Gastric Cancer
China Health Promotion Foundation/the Second Affiliated Hospital of Zhejiang University, School of Medicine
NCT04989153CI-TRIAL-00053082unknownClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Pepsinogens (PGs) can be used for gastric cancer (GC) screening, but the cutoff levels vary among studies, and PG levels are influenced by numerous factors. To examine the diagnostic value of PG levels and Helicobacter pylori (Hp) status for GC and precancerous lesions screening in asymptomatic individuals undergoing health checkup in China.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Gastric Cancer | Malignant Gastric Neoplasm | CURATED_BROADER | 0.80 |
| Helicobacter Pylori Infection | — | UNRESOLVED | — |
| Precancerous Lesion | Gastric Neoplasm | PROBABILISTIC | 0.70 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| pepsinogen | Diagnostic Test | — | UNRESOLVED |
Design
Arms and outcomes
Arms (4)
- label
- non-atrophic gastritis
- description
- No atrophic gastritis, The OLGA-0 group;OLGA :Operative Link on Gastritis Assessment)
- label
- mild-moderate atrophic gastritis
- description
- The OLGA I-II group;OLGA :Operative Link on Gastritis Assessment)
- label
- severe atrophic gastritis
- description
- The OLGA III-IV group;OLGA :Operative Link on Gastritis Assessment)
- interventionNames
- Diagnostic Test: pepsinogen
- label
- gastric cancer
- description
- gastric cancer
- interventionNames
- Diagnostic Test: pepsinogen
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 25 Years
- Maximum age
- 75 Years
Show eligibility criteria text
Inclusion Criteria: intention to undergo gastroscopy during health checkup examination 25-75 years of age. Exclusion Criteria: a history of gastric ulcer, gastric polyp, or GC a history of gastrectomy treatment with a proton pump inhibitor in the last month contraindications to gastroscopy a history of Hp eradication a history of abdominal pain, abdominal distention, belching, acid reflux, nausea and other digestive tract symptoms within 1 month incomplete data.
References
Publications (0)
Data not yet available
No reference posted for this study.