Clinical trial · Interventional
Lung Screening in People Cured of Hodgkin Lymphoma
Lung Screening for Hodgkin Lymphoma Survivors: a Feasibility Study
NCT04986189CI-TRIAL-00082200completedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
A single site non-commercial study in which people treated for Hodgkin lymphoma survivors will be invited to have a single low dose CT of thorax for lung cancer screening
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Hodgkin Lymphoma | Hodgkin Lymphoma | ONTOLOGY_EXACT | 0.90 |
| Lung Cancer | Malignant Lung Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Low dose CT thorax | Diagnostic Test | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- OTHER
- label
- Invitation to have a low dose CT thorax
- description
- All participants are invited to undergo a low dose CT thorax
- interventionNames
- Diagnostic Test: Low dose CT thorax
Primary outcomes (1)
- measure
- Primary outcome: the lung cancer screening uptake rate among eligible individuals invited to the study
- timeFrame
- Measured 6 months after recruitment begins when all interested participants have undergone a full eligibility check and those eligible have undergone their baseline low dose CT scan
- description
- Feasibility outcome
Secondary outcomes (13)
- measure
- Decisional conflict scores in those who receive the decision aid measured using the validated Decisional Conflict Scale (score 0-100 with higher score representing higher levels of decisional conflict)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 80 Years
Show eligibility criteria text
Inclusion Criteria: * Aged 18-80 * 5 year or more survivor of HL * Any of: a) treated with radiotherapy for HL with radiation dose to the lung b) an alkylating agent containing chemotherapy regimen known to increase lung cancer risk * Living within approximately 40 miles of The Christie Hospital Exclusion Criteria: * Previous diagnoses of malignant neoplasm of trachea, bronchus, lung, thymus or pleura * A current diagnosis of metastatic cancer * Residents in nursing homes or housebound * Had a CT scan of the thorax within the last 12 months * Pregnant women * Unable to provide consent
References
Publications (1)
- DERIVEDBroadbent R, Crosbie P, Armitage CJ, Taylor B, Tenant S, Mercer J, Radford J, Linton K. Pilot study of lung cancer screening for survivors of Hodgkin lymphoma. Haematologica. 2024 Oct 1;109(10):3305-3313. doi: 10.3324/haematol.2023.283287. PMID 37981893