Clinical trial · Interventional
Abdominal Drainage, Postoperative Antibiotico-prophylaxis and CME With D3 Lyphadenectomy Effect on Gastrointestinal Function in Laparoscopic Right Hemicolectomy With Intracorporeal Anastomosis for Right Colon Cancer
NCT04977882CI-TRIAL-00071640completedEarly Phase 1ClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Monocentric, two-level factorial, parallel-arm, pilot randomized clinical trial, conducted comparing patients undergoing laparoscopic right hemicolectomy with ICA for right colon cancer in a single unit of a teaching hospital: Minimally Invasive Surgery Unit, Department of Surgical Sciences, Policlinico Tor Vergata, Rome, Italy.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Colon Cancer | Malignant Colon Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (4)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| abdominal drainage | Procedure | — | UNRESOLVED |
| Laparoscopic radical right colectomy with CME and D3 lymphadenectomy (RRC) | Procedure | — | UNRESOLVED |
| Laparoscopic standard D2 right hemicolectomy (STANDARD) | Procedure | — | UNRESOLVED |
| Postoperative antibiotico-prophylaxis | Drug | — | UNRESOLVED |
Design
Arms and outcomes
Arms (3)
- type
- EXPERIMENTAL
- label
- Abdominal drainage
- description
- 19 Fr abdominal drainage placed intraoperatevely in right paracolic gutter
- interventionNames
- Procedure: abdominal drainage
- Procedure: Laparoscopic radical right colectomy with CME and D3 lymphadenectomy (RRC)
- Procedure: Laparoscopic standard D2 right hemicolectomy (STANDARD)
- type
- EXPERIMENTAL
- label
- Postoperative antibiotico-prophylaxis
- description
- postoperative antibiotico-prophylaxis with Ceftriaxone 2gr and Metronidazole 1.5gr
- interventionNames
- Drug: Postoperative antibiotico-prophylaxis
- Procedure: Laparoscopic radical right colectomy with CME and D3 lymphadenectomy (RRC)
- Procedure: Laparoscopic standard D2 right hemicolectomy (STANDARD)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Right colon cancer * Intracorporeal anastomosis * Laparoscopic surgery * Elective surgery * informed consent signed Exclusion Criteria: * below 18 years old * IBD * ASA IV * T4b * Metastatic disease * Preoperative steroids * Conversion to open surgery * Emergency surgery * concomitant major operation * preoperative infective status * benign disease
References
Publications (1)
- DERIVEDSica GS, Siragusa L, Pirozzi BM, Sorge R, Baldini G, Fiorani C, Guida AM, Bellato V, Franceschilli M. Gastrointestinal functions after laparoscopic right colectomy with intracorporeal anastomosis: a pilot randomized clinical trial on effects of abdominal drain, prolonged antibiotic prophylaxis, and D3 lymphadenectomy with complete mesocolic excision. Int J Colorectal Dis. 2024 Jul 6;39(1):102. doi: 10.1007/s00384-024-04657-0. PMID 38970713