Clinical trial · Observational
Patogenic Mutation in 5 Genes
Genomic Landscape of APC, KRAS, TP53, PIK3CA, and MLH1 in Colorectal
NCT04976439CI-TRIAL-00052887completedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This is a pathogenic mutation profile of colorectal patients specifically in 5 genes, i.e. APC, TP53, PIK3CA, KRAS, and MLH1. Single nucleotide variants identified were synchronized with patients' characteristics.
Conditions
Conditions (6)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| APC Gene Mutation | — | UNRESOLVED | — |
| Colorectal Cancer | Malignant Colorectal Neoplasm | CURATED_BROADER | 0.80 |
| KRAS Mutation-Related Tumors | Colorectal Neoplasm | PROBABILISTIC | 0.70 |
| MLH1 Gene Mutation | — | UNRESOLVED | — |
| PIK3CA Gene Mutation | — | UNRESOLVED | — |
| TP53 Gene Mutation | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| co-occuring mutation | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (5)
- label
- Age
- interventionNames
- Other: co-occuring mutation
- label
- Grade
- interventionNames
- Other: co-occuring mutation
- label
- Tumor location
- interventionNames
- Other: co-occuring mutation
- label
- Stage
- interventionNames
- Other: co-occuring mutation
- label
- Lymphovascular invasion
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * FFPE samples fullfilling purity criterion and pass quality control Exclusion Criteria: * none
References
Publications (0)
Data not yet available
No reference posted for this study.