Clinical trial · Observational
Impact of E-cigarette Use on the Body
The Emerging Adulthood Health Project
NCT04972513CI-TRIAL-00106188active not recruitingClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This study examines how electronic (e)-cigarette use impacts the body, by studying both users and non-users of e-cigarettes. Early evidence indicates that e-cig users experience adverse health effects. Results of this study may help policy-makers develop standards for different types of tobacco.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cigarette Smoking-Related Carcinoma | Cigarette Smoking-Related Carcinoma | ONTOLOGY_EXACT | 0.98 |
Interventions
Interventions (6)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Biospecimen Collection | Procedure | — | UNRESOLVED |
| Endothelial function | Procedure | — | UNRESOLVED |
| Nitric Oxide Breath Test | Procedure | — | UNRESOLVED |
| Oscillometry | Procedure | — | UNRESOLVED |
| Spirometry | Procedure | — | UNRESOLVED |
| Survey Administration | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- Prevention (survey, breathe tests, biospecimen collection)
- description
- Participants undergo computer-based spirometry testing, nitric oxide breath testing, airwave oscillometry, and an assessment of endothelial function. Participants will undergo collection of blood. Current e-cigarette users also vape their own e-cigarette device for 30 minutes.
- interventionNames
- Procedure: Biospecimen Collection
- Procedure: Nitric Oxide Breath Test
- Procedure: Oscillometry
- Procedure: Spirometry
- Other: Survey Administration
- Procedure: Endothelial function
Primary outcomes (4)
- measure
- Airway inflammation as assessed by exhaled nitric oxide
- timeFrame
- Procedure will last approximately 3 minutes; the procedure will occur twice during the laboratory session (separated by approximately 60 minutes)
- description
- Exhaled nitric oxide will be measured in parts per billion (ppb)
- measure
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 15 Years
- Maximum age
- 25 Years
Show eligibility criteria text
Inclusion Criteria: * 75 e-cig users and 75 never-users * No self-reported diagnosis of lung disease (e.g., coronavirus disease-2019 \[COVID-19\], pneumonia, cystic fibrosis) * No history of cardiac event or distress * Not currently breastfeeding, pregnant, or planning to become pregnant (e-cig users only; will be confirmed via pregnancy test)
References
Publications (0)
Data not yet available
No reference posted for this study.