Clinical trial · Interventional
Feasibility and Efficacy of a Digital Neurotherapy Protocol for Management of Depression, Cognition, and Quality of Life in Cancer Survivors
Feasibility and Efficacy of a Digital Neurotherapy Protocol for Management of Depression, Cognition, and Quality of Life in Patients With Major Medical Illnesses
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This is a prospective, randomized clinical study to evaluate the feasibility and efficacy of a digital neurotherapy on depression, cognition, and quality of life in two groups of patients with major medical illness: 1) a sample of cancer survivors, and 2) a sample of patients with end stage kidney disease (ESKD) on dialysis.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cognition | — | UNRESOLVED | — |
| Depression | — | UNRESOLVED | — |
| Quality of Life | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Digital neurotherapy (DNT) Treatment | Behavioral | — | UNRESOLVED |
| Wait list control group | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Digital neurotherapy (DNT) Treatment
- description
- The experimental group will have 8 weeks of DNT 4 times a week for 30 minutes in the participant's home. The computer-presented training will be done on the participants' tablets or personal computers with the Rejuvenate brain training program
- interventionNames
- Behavioral: Digital neurotherapy (DNT) Treatment
- type
- ACTIVE_COMPARATOR
- label
- Wait list control group
- description
- Waiting-list control group participants will be offered 8 weeks of DNT training at the completion of the final outcome assessment.
- interventionNames
- Behavioral: Wait list control group
Primary outcomes (11)
- measure
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Cancer Survivor Group Inclusion Criteria: 1. Provision of signed and date informed consent form. 2. Stated willingness to comply with all study procedures and availability for the durationof the study. 3. Associated with Smilow Cancer Hospital with a diagnosis for cancer 4. Have received chemotherapy, and/or radiation treatment, and/or immuno therapy treatment for cancer 5. Able to understand and read English Exclusion Criteria: 1. Stage 4 cancer 2. Brain cancer 3. Diagnosis of serious mental illness (ie, psychosis) 4. Cognitive impairment (ie, diagnosed dementia, intellectual development disorder) 5. Hearing or vision insufficient to do the computer exercises. ESKD Group Inclusion Criteria: 1. Associated with Yale Nephrology practice and receiving in-center hemodialysis treatment 2. Have received hemodialysis for at least one month from start of outpatient dialysis and attended 10 of first 12 visits. Exclusion Criteria: 1. Diagnosis of serious mental illness (ie, psychosis) 2. Cognitive Impairment (ie, diagnosed dementia, intellectual development disorder) 3. Hearing or vision insufficient to do the computer exercises
References
Publications (0)
Data not yet available