Clinical trial · Interventional
Partial Scalp Block in Posterior Fossa Surgery
Partial Scalp Block Versus Fentanyl Infusion in Patients Undergoing Posterior Fossa Surgery Under General Anesthesia. A Randomized Control Trial
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Pain in patients undergoing posterior fossa surgery is regarded as more intense when compared to pain in patients undergoing supratentorial cranial surgeries. It may result in a rise in blood pressure and heart rate leading to serious effects as increased intracranial pressure and intracranial hemorrhage. For a long time, the control of pain has been the role of opioids. However, the use of opioids is not devoid of side effects. Hence, combining other techniques as partial scalp block with general anesthesia may be beneficial in controlling hemodynamics and decreasing the amount of opioids used without sacrificing the good quality of analgesia and anesthesia.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Posterior Fossa Tumor | Posterior Fossa Neoplasm | ALIAS | 0.90 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Fentanyl | Drug | — | UNRESOLVED |
| Partial scalp block | Drug | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Partial scalp block
- description
- Bilateral block of the greater lesser and third occipital nerves using bupivacaine 0.25% with epinephrine 1:200,000
- interventionNames
- Drug: Partial scalp block
- type
- ACTIVE_COMPARATOR
- label
- Fentanyl group
- description
- Fentanyl infusion will be administered till time of dural closure
- interventionNames
- Drug: Fentanyl
Primary outcomes (1)
- measure
- Systolic blood pressure at time of skin incision
- timeFrame
- During surgery, 1 min after skin incision
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 21 Years
- Maximum age
- 55 Years
Show eligibility criteria text
Inclusion Criteria: * Physical status ASA I and ASA ll. * Males and females between the ages of 21 and 55. * Patients undergoing posterior fossa Surgeries. * Patients with GCS ≥14 * Patients undergoing operation in prone position Exclusion Criteria: * Patient refusal. * Patients with a history of allergy to opioids or local anesthetics * GCS (Glasgow coma score) ≤13 upon emergence from anesthesia. * Patients who will need post-operative ventilation * Patients who had previous craniotomies * Patients with contraindication to regional anaesthesia e.g.: local sepsis, * Patients with pre-existing peripheral neuropathies and coagulopathy. * Patients who will develop intraoperative surgical complications * Operations lasting more than 5 hours.
References
Publications (4)
- BACKGROUNDVadivelu N, Kai AM, Tran D, Kodumudi G, Legler A, Ayrian E. Options for perioperative pain management in neurosurgery. J Pain Res. 2016 Feb 10;9:37-47. doi: 10.2147/JPR.S85782. eCollection 2016. PMID 26929661
- BACKGROUNDPinosky ML, Fishman RL, Reeves ST, Harvey SC, Patel S, Palesch Y, Dorman BH. The effect of bupivacaine skull block on the hemodynamic response to craniotomy. Anesth Analg. 1996 Dec;83(6):1256-61. doi: 10.1097/00000539-199612000-00022. PMID 8942596
- BACKGROUNDJian M, Li X, Wang A, Zhang L, Han R, Gelb AW. Flurbiprofen and hypertension but not hydroxyethyl starch are associated with post-craniotomy intracranial haematoma requiring surgery. Br J Anaesth. 2014 Nov;113(5):832-9. doi: 10.1093/bja/aeu185. Epub 2014 Jun 25. PMID 24966149
- RESULTOsborn I, Sebeo J. "Scalp block" during craniotomy: a classic technique revisited. J Neurosurg Anesthesiol. 2010 Jul;22(3):187-94. doi: 10.1097/ANA.0b013e3181d48846. PMID 20479675