Clinical trial · Observational
The Role of Vascular Reconstruction in the Setting of Pelvic Exenteration
A Review of Surgical Outcomes for Patients Undergoing En-bloc Vascular Resection and Reconstruction as Part of Exenteration for Advanced Pelvic Malignancy
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Local invasion or abutment of a major vascular structure was once a major deterrent to planned oncological resection. Improvements in radiological assessment and vascular surgical techniques have enabled resection of major blood vessels where focally involved. However, most of this has been conducted in the context of cancers of sarcomatous, hepaticopancreaticobilary or otolaryngological origin, with little evidence detailing the experience in the context of pelvic malignancy. The aim of this retrospective review is to examine the indications for, techniques used and surgical outcomes of vascular reconstruction in the setting of pelvic exenterative surgery.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Vascular Reconstruction in Pelvic Exenterative Surgery | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Vascular resection/reconstruction | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- Vascular reconstruction
- description
- Patients who have undergone resection with or without reconstruction of a major blood vessel in the context of surgery for a locally advanced pelvic malignancy. This will mostly refer to patients who have had resection/reconstruction of their internal iliac vessels, or less likely common iliacs.
- interventionNames
- Procedure: Vascular resection/reconstruction
Primary outcomes (1)
- measure
- Morbidity
- timeFrame
- July 2016 - July 2021
- description
- Post-operative complications (\<30 days), as measured by the Clavien-Dindo scale
Secondary outcomes (5)
- measure
- Blood loss
- timeFrame
- July 2016 - July 2021
- description
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Histologically proven locally advanced or recurrent pelvic cancer (all subtypes, RECTAL, UROLOGICAL, GYNAE, SARCOMA) * Aged over 18 years * Undergoing a multi-visceral extended pelvic resection * Requiring a vascular resection with or without the need for reconstruction as part of pelvic exenteration Exclusion Criteria: * Strong evidence of metastatic or peritoneal disease * No histological evidence of vascular structures resected at time of operation * Insufficient patient follow-up (Minimum of 30 days) * Insufficient information on post-operative follow-up of graft patency/function
References
Publications (0)
Data not yet available